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• W2022852494 abstract "No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Jul 2002The Relationship of Detrusor Instability and Symptoms With Objective Parameters Used for Diagnosing Bladder Outlet Obstruction: A Prospective Study Bassem S. Wadie, El-Husseiny E. Ebrahim, and Mohamed A. Gomha Bassem S. WadieBassem S. Wadie More articles by this author , El-Husseiny E. EbrahimEl-Husseiny E. Ebrahim More articles by this author , and Mohamed A. GomhaMohamed A. Gomha More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)64845-8AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Detrusor instability is a common urodynamic finding in patients with prostatic obstruction. In prospective fashion we evaluated detrusor instability in patients with lower urinary tract symptoms attributable to benign prostatic hyperplasia and determined its possible association with the degree of obstruction. Materials and Methods: A total of 459 men with a mean age plus or minus standard deviation of 60.4 ± 9.4 years who were investigated for lower urinary tract symptoms at our facility answered an Arabic standardized version of International Prostate Symptom Score and underwent simple uroflowmetry, outpatient cystoscopy and transrectal ultrasound. Invasive urodynamics, including filling and voiding cystometry, was done with pressure flow analysis according to the Schäfer nomogram. Statistical significance was tested by the Mann-Whitney U and Wilcoxon rank sum tests. Results: Of the 459 patients 108 (23.5%) had detrusor instability. Instability significantly affected patient symptom score and conception of quality of life. Moreover, instability significantly affected the degree of obstruction, as measured by the maximum flow rate, post-void residual urine, prostate volume and Schäfer grade of obstruction. Conclusions: Detrusor instability affects patient symptoms and quality of life. It also signifies a more severe degree of obstruction in male patients with lower urinary tract symptoms and bladder outlet obstruction due to benign prostatic hyperplasia. References 1 : Br J Urol1976; 48: 39. Google Scholar 2 : Terminology related to neuromuscular dysfunction of the lower urinary tract Produced by the International Continence Society. Br J Urol1981; 53: 333. Google Scholar 3 : Prostatism. I. The correlation between symptoms, cystometric and urodynamic findings. Scand J Urol Nephrol1979; 13: 229. Google Scholar 4 : Detrusor hyperreflexia in benign infravesical obstruction. A cystometric study. J Urol1976; 115: 532. Link, Google Scholar 5 : Obstructed and unobstructed prostatic obstruction. A plea for urodynamic objectivation of bladder outflow obstruction in benign prostatic hyperplasia. World J Urol1989; 6: 198. Google Scholar 6 : A simplified graphic procedure for detailed analysis of detrusor and outlet function during voiding. Neurourol Urodyn1989; 8: 405. Google Scholar 7 : Symptom indices in bladder outlet obstruction. Br J Urol1996; 77: 494. Google Scholar 8 : The 2nd International Consultation on Benign Prostatic Hyperplasia (BPH). Jersey: Scientific Communication International Ltd.1993: 553. Google Scholar 9 : The relationship of the International Prostate Symptom Score and objective parameters for diagnosing bladder outlet obstruction. Part I: when statistics fail. J Urol2001; 165: 32. Link, Google Scholar 10 : Relationship of symptoms of prostatism to commonly used physiological and anatomical measures of severity of benign prostatic hyperplasia. J Urol1993; 150: 351. Abstract, Google Scholar 11 : Clinical diagnosis of bladder outlet obstruction in patients with benign prostatic enlargement and lower urinary tract symptoms: development and urodynamic validation of a clinical prostate score for the objective diagnosis of bladder outlet obstruction. J Urol1996; 155: 1649. Link, Google Scholar 12 : The interpretation of conventional urodynamics. In: Urodynamics: Principles, Practice and Application. Edited by . New York: Churchill Livingstone1994: 111. chapt. 9. Google Scholar 13 : Quality of Life Measurement in Health Care. A review of measures, and population norms for the UK SF-36. United Kingdom: University of Oxford Health Services Research Unit1993: 1. Google Scholar 14 : Bladder outflow obstruction in the male. In: Urodynamics: Principles, Practice and Application. Edited by . New York: Churchill Livingstone1994: 233. chapt. 17. Google Scholar 15 : Structural basis of geriatric voiding dysfunction. I. Methods of a prospective ultrastructural/urodynamic study and an overview of the findings. J Urol1993; 150: 1650. Link, Google Scholar 16 : The significance of age on symptoms and urodynamic- and cystoscopic findings in benign prostatic hypertrophy. Urol Res1987; 15: 355. Google Scholar 17 : Detrusor instability in bladder outlet obstruction. Neurourol Urodyn1985; 4: 317. Google Scholar 18 : Detrusor instability and bladder outflow obstruction. Evidence for a correlation between the severity of obstruction and the presence of instability. Br J Urol1988; 61: 420. Google Scholar From the Mansoura Urology and Nephrology Center, Mansoura, Egypt© 2002 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byZhang X, Li G, Wei X, Mo X, Hu L, Zha Y and Hou J (2018) Resistive Index of Prostate Capsular Arteries: A Newly Identified Parameter to Diagnose and Assess Bladder Outlet Obstruction in Patients with Benign Prostatic HyperplasiaJournal of Urology, VOL. 188, NO. 3, (881-887), Online publication date: 1-Sep-2012.DORKIN T, LEONARD A and PICKARD R (2018) Can Bladder Outflow Obstruction be Diagnosed From Pressure Flow Analysis of Voiding Initiated by Involuntary Detrusor Overactivity?Journal of Urology, VOL. 170, NO. 4 Part 1, (1234-1236), Online publication date: 1-Oct-2003. Volume 168Issue 1July 2002Page: 132-134 Advertisement Copyright & Permissions© 2002 by American Urological Association, Inc.Keywordsprostatic hyperplasiamuscle, smoothbladder neck obstructionbladderquestionnairesMetricsAuthor Information Bassem S. Wadie More articles by this author El-Husseiny E. Ebrahim More articles by this author Mohamed A. Gomha More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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