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- W2022862336 abstract "In this review, we describe the non-antibody-mediated functions of B cells within the immune system. In addition to antibody production, B cells also present antigen to T cells, programme T cell differentiation and regulate effector T cell responses and much of this is mediated by the cytokines they make. We focus on the potential of B cells to perform these functions simply as a result of activation via ‘innate’ receptors (e.g. Toll-like receptors) and often independently of BCR ligation. We feel an appreciation of these broad and often antigen-nonspecific functions is important at a time when there is an increasing use of B cell depletion as a therapy for autoimmune disease." @default.
- W2022862336 created "2016-06-24" @default.
- W2022862336 creator A5039308139 @default.
- W2022862336 creator A5071842424 @default.
- W2022862336 creator A5091018287 @default.
- W2022862336 date "2007-12-01" @default.
- W2022862336 modified "2023-09-29" @default.
- W2022862336 title "Innate responses of B cells" @default.
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- W2022862336 doi "https://doi.org/10.1002/eji.200737728" @default.
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