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- W2022863757 abstract "Hydroxylchalcone are known to act on various physiological targets. In this study, a series of nine hydroxychalcones were synthesized via the aldol condensation with the aim of obtaining bioactive small molecules. Their structures were characterized by NMR spectra. The anti-breast cancer activity evaluation indicated the monohydroxychalcones exhibited the better anti-proliferative effect than dihydroxylchalcones against MDA-MB-231 cells, and the compound 3b showed the best anti-breast cancer activities at 18 μM. The bioactive compounds might be used to develop as potential anti-breast cancer agents." @default.
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- W2022863757 date "2013-10-01" @default.
- W2022863757 modified "2023-09-26" @default.
- W2022863757 title "Study on Biological Materials with Facile Synthesis and Anti-Breast Cancer Activities of Hydroxylchalcones Derivatives" @default.
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- W2022863757 doi "https://doi.org/10.4028/www.scientific.net/amr.830.459" @default.
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