Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022871154> ?p ?o ?g. }
- W2022871154 endingPage "194" @default.
- W2022871154 startingPage "190" @default.
- W2022871154 abstract "Liposuction is one of the more common elective surgical procedures in the US and is supposed to be on the increase. There are no reported studies specifically addressing the metabolic sequelae of liposuction in obesity. The aim of the present study was to investigate the role of large-volume liposuction on insulin resistance and circulating inflammatory markers in obese people. Thirty healthy premenopausal obese (body mass index (BMI) from 30 to 45) and 30 age-matched normal weight (BMI<25) women were studied. In obese women, insulin sensitivity, as measured by the Homeostasis Model Assessment (HOMA=fasting plasma glucose x fasting serum insulin divided by 25), as well as serum adiponectin, the novel adipocytokine with insulin sensitising properties, were significantly lower, as compared with nonobese women (p<0.01), indicating insulin resistance; on the contrary, serum concentrations of the proinflammatory cytokines IL-6, IL-18 and TNF-alpha, as well as the sensitive marker of inflammation C-reactive protein, were significantly higher (p<0.01). All obese women were submitted to a single large volume liposuction (superwet technique): the mean aspirate volume was 3540 ml (range 2550-4670), corresponding to a net lipid loss of 2.7+/-0.7 kg (mean+/-SD). After six months of stable body weight after liposuction, women were less insulin resistant (p<0.05), had reduced concentrations of IL-6, IL-18, TNF-alpha and CRP (p<0.05-0.02), and increased serum levels of adiponectin (p<0.02) and HDL-cholesterol (p<0.05). There was a significant correlation between the amount of fat aspirate and changes in HOMA (r=0.28, p<0.05), TNF-alpha (r=0.31, p<0.02), and adiponectin (r=-0.34, p<0.02), as well as between the decrease in TNF-alpha and the increase in adiponectin after the surgical procedure (r=-0.45, p<0.01). Our study demonstrates that liposuction is safe and free of metabolic sequelae in obese women, pending a careful screening of the patient. Moreover, it is associated with amelioration of insulin resistance and reduced circulating markers of vascular inflammation which may help obese subjects to reduce their cardiovascular risk." @default.
- W2022871154 created "2016-06-24" @default.
- W2022871154 creator A5018704681 @default.
- W2022871154 creator A5033863145 @default.
- W2022871154 creator A5034262325 @default.
- W2022871154 creator A5052044111 @default.
- W2022871154 creator A5059360279 @default.
- W2022871154 creator A5059718849 @default.
- W2022871154 creator A5091616109 @default.
- W2022871154 date "2004-04-01" @default.
- W2022871154 modified "2023-10-17" @default.
- W2022871154 title "Effect of liposuction on insulin resistance and vascular inflammatory markers in obese women" @default.
- W2022871154 cites W1927710737 @default.
- W2022871154 cites W1976007672 @default.
- W2022871154 cites W1988449027 @default.
- W2022871154 cites W1994961575 @default.
- W2022871154 cites W2012784530 @default.
- W2022871154 cites W2022801078 @default.
- W2022871154 cites W2023731005 @default.
- W2022871154 cites W2052437432 @default.
- W2022871154 cites W2054893928 @default.
- W2022871154 cites W2058610272 @default.
- W2022871154 cites W2095726149 @default.
- W2022871154 cites W2098065069 @default.
- W2022871154 cites W2107863336 @default.
- W2022871154 cites W2109106098 @default.
- W2022871154 cites W2119316150 @default.
- W2022871154 cites W2138220577 @default.
- W2022871154 cites W2139613376 @default.
- W2022871154 cites W2155952282 @default.
- W2022871154 cites W2160234571 @default.
- W2022871154 cites W2244492297 @default.
- W2022871154 cites W2916596946 @default.
- W2022871154 cites W4245570177 @default.
- W2022871154 doi "https://doi.org/10.1016/j.bjps.2003.12.010" @default.
- W2022871154 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15006519" @default.
- W2022871154 hasPublicationYear "2004" @default.
- W2022871154 type Work @default.
- W2022871154 sameAs 2022871154 @default.
- W2022871154 citedByCount "144" @default.
- W2022871154 countsByYear W20228711542012 @default.
- W2022871154 countsByYear W20228711542013 @default.
- W2022871154 countsByYear W20228711542014 @default.
- W2022871154 countsByYear W20228711542015 @default.
- W2022871154 countsByYear W20228711542016 @default.
- W2022871154 countsByYear W20228711542017 @default.
- W2022871154 countsByYear W20228711542018 @default.
- W2022871154 countsByYear W20228711542019 @default.
- W2022871154 countsByYear W20228711542020 @default.
- W2022871154 countsByYear W20228711542021 @default.
- W2022871154 countsByYear W20228711542022 @default.
- W2022871154 countsByYear W20228711542023 @default.
- W2022871154 crossrefType "journal-article" @default.
- W2022871154 hasAuthorship W2022871154A5018704681 @default.
- W2022871154 hasAuthorship W2022871154A5033863145 @default.
- W2022871154 hasAuthorship W2022871154A5034262325 @default.
- W2022871154 hasAuthorship W2022871154A5052044111 @default.
- W2022871154 hasAuthorship W2022871154A5059360279 @default.
- W2022871154 hasAuthorship W2022871154A5059718849 @default.
- W2022871154 hasAuthorship W2022871154A5091616109 @default.
- W2022871154 hasConcept C126322002 @default.
- W2022871154 hasConcept C134018914 @default.
- W2022871154 hasConcept C141071460 @default.
- W2022871154 hasConcept C164027704 @default.
- W2022871154 hasConcept C171089720 @default.
- W2022871154 hasConcept C2776782570 @default.
- W2022871154 hasConcept C2776914184 @default.
- W2022871154 hasConcept C2777391703 @default.
- W2022871154 hasConcept C2778096610 @default.
- W2022871154 hasConcept C2778163477 @default.
- W2022871154 hasConcept C2778270857 @default.
- W2022871154 hasConcept C2779306644 @default.
- W2022871154 hasConcept C2780140801 @default.
- W2022871154 hasConcept C2780221984 @default.
- W2022871154 hasConcept C511355011 @default.
- W2022871154 hasConcept C71924100 @default.
- W2022871154 hasConceptScore W2022871154C126322002 @default.
- W2022871154 hasConceptScore W2022871154C134018914 @default.
- W2022871154 hasConceptScore W2022871154C141071460 @default.
- W2022871154 hasConceptScore W2022871154C164027704 @default.
- W2022871154 hasConceptScore W2022871154C171089720 @default.
- W2022871154 hasConceptScore W2022871154C2776782570 @default.
- W2022871154 hasConceptScore W2022871154C2776914184 @default.
- W2022871154 hasConceptScore W2022871154C2777391703 @default.
- W2022871154 hasConceptScore W2022871154C2778096610 @default.
- W2022871154 hasConceptScore W2022871154C2778163477 @default.
- W2022871154 hasConceptScore W2022871154C2778270857 @default.
- W2022871154 hasConceptScore W2022871154C2779306644 @default.
- W2022871154 hasConceptScore W2022871154C2780140801 @default.
- W2022871154 hasConceptScore W2022871154C2780221984 @default.
- W2022871154 hasConceptScore W2022871154C511355011 @default.
- W2022871154 hasConceptScore W2022871154C71924100 @default.
- W2022871154 hasIssue "3" @default.
- W2022871154 hasLocation W20228711541 @default.
- W2022871154 hasLocation W20228711542 @default.
- W2022871154 hasOpenAccess W2022871154 @default.
- W2022871154 hasPrimaryLocation W20228711541 @default.
- W2022871154 hasRelatedWork W2073817778 @default.