Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022871446> ?p ?o ?g. }
- W2022871446 endingPage "281" @default.
- W2022871446 startingPage "261" @default.
- W2022871446 abstract "To initiate the establishment of an epitheliochorial placenta, the developing porcine conceptuses contact the maternal endometrium on its mesometrial side. The porcine conceptuses secrete estrogens which, together with circulating maternal hormones, govern variations in the structure as well as expression and levels of steroid receptors and growth factors during early pregnancy. Mesometrial samples of endometrium or placenta were collected from 15 early pregnant (8–30 days after the onset of estrus) and six cycling (days 1–14) gilts. The variations in tissue morphology and immunohistochemical localization of insulin-like growth factor-I (IGF-I) were related to the tissue levels (by enzyme immunoassay) of receptors for estrogen (ER) and progesterone (PR), as well as mRNA (by solution hybridization) concentrations for the two receptors and IGF-I. IGF-I immunoreactivity was present in samples from all animals, being principally located in maternal epithelium, trophoblast, endothelium and vascular smooth muscle; the latter showing the strongest labeling. The levels of receptor proteins, as well as mRNAs, were highest in the non-pregnant animals at estrus and metestrus. The pregnant animals showed decreasing concentrations to consistently low levels after day 14. Temporal changes in the studied parameters were clearly coincidental with the peak (days 13–14) in conceptus estrogen secretion, e.g. the more uniform IGF-I immunolabeling in the uterine glands (days 8–13) compared with the later stages studied; the conspicuous accumulation and release of secretory vesicles in the endometrial glands (days 8–13), marking the change in secretory quality and quantity, leading to a gradual shift from histotrophic to hemotrophic nutrition of the conceptuses, and finally, the peaking level of IGF-I mRNA in the pregnant endometrium (days 12–13) which decreased considerably thereafter. It is concluded that IGF-I activity in the porcine uterus changes with the early development of the placenta." @default.
- W2022871446 created "2016-06-24" @default.
- W2022871446 creator A5009756175 @default.
- W2022871446 creator A5036162514 @default.
- W2022871446 creator A5072357573 @default.
- W2022871446 creator A5074163488 @default.
- W2022871446 creator A5088044677 @default.
- W2022871446 creator A5091083841 @default.
- W2022871446 date "1997-04-01" @default.
- W2022871446 modified "2023-10-18" @default.
- W2022871446 title "Insulin-like growth factor-I in the porcine endometrium and placenta: Localization and concentration in relation to steroid influence during early pregnancy" @default.
- W2022871446 cites W1775749144 @default.
- W2022871446 cites W1963853606 @default.
- W2022871446 cites W1966656070 @default.
- W2022871446 cites W1970271824 @default.
- W2022871446 cites W1973553476 @default.
- W2022871446 cites W1978734327 @default.
- W2022871446 cites W1984344088 @default.
- W2022871446 cites W1993138705 @default.
- W2022871446 cites W1997113017 @default.
- W2022871446 cites W1998100866 @default.
- W2022871446 cites W2002940954 @default.
- W2022871446 cites W2006975964 @default.
- W2022871446 cites W2027137127 @default.
- W2022871446 cites W2029628645 @default.
- W2022871446 cites W2032744349 @default.
- W2022871446 cites W2042891199 @default.
- W2022871446 cites W2043047016 @default.
- W2022871446 cites W2044828529 @default.
- W2022871446 cites W2050075831 @default.
- W2022871446 cites W2056685751 @default.
- W2022871446 cites W2057234936 @default.
- W2022871446 cites W2070726745 @default.
- W2022871446 cites W2075800748 @default.
- W2022871446 cites W2075970737 @default.
- W2022871446 cites W2077285600 @default.
- W2022871446 cites W2077758233 @default.
- W2022871446 cites W2078119356 @default.
- W2022871446 cites W2079177811 @default.
- W2022871446 cites W2083330284 @default.
- W2022871446 cites W2084374407 @default.
- W2022871446 cites W2088259163 @default.
- W2022871446 cites W2089318261 @default.
- W2022871446 cites W2089364169 @default.
- W2022871446 cites W2107268558 @default.
- W2022871446 cites W2119536364 @default.
- W2022871446 cites W2131991258 @default.
- W2022871446 cites W2140877033 @default.
- W2022871446 cites W2144217231 @default.
- W2022871446 cites W2155748935 @default.
- W2022871446 cites W2165655523 @default.
- W2022871446 cites W2172214857 @default.
- W2022871446 cites W2409299122 @default.
- W2022871446 cites W330945565 @default.
- W2022871446 cites W4235256413 @default.
- W2022871446 cites W4245635197 @default.
- W2022871446 cites W4294216491 @default.
- W2022871446 doi "https://doi.org/10.1016/s0378-4320(96)01610-7" @default.
- W2022871446 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9231265" @default.
- W2022871446 hasPublicationYear "1997" @default.
- W2022871446 type Work @default.
- W2022871446 sameAs 2022871446 @default.
- W2022871446 citedByCount "45" @default.
- W2022871446 countsByYear W20228714462013 @default.
- W2022871446 countsByYear W20228714462014 @default.
- W2022871446 countsByYear W20228714462016 @default.
- W2022871446 countsByYear W20228714462018 @default.
- W2022871446 countsByYear W20228714462022 @default.
- W2022871446 crossrefType "journal-article" @default.
- W2022871446 hasAuthorship W2022871446A5009756175 @default.
- W2022871446 hasAuthorship W2022871446A5036162514 @default.
- W2022871446 hasAuthorship W2022871446A5072357573 @default.
- W2022871446 hasAuthorship W2022871446A5074163488 @default.
- W2022871446 hasAuthorship W2022871446A5088044677 @default.
- W2022871446 hasAuthorship W2022871446A5091083841 @default.
- W2022871446 hasConcept C121608353 @default.
- W2022871446 hasConcept C126322002 @default.
- W2022871446 hasConcept C134018914 @default.
- W2022871446 hasConcept C16685009 @default.
- W2022871446 hasConcept C170493617 @default.
- W2022871446 hasConcept C172680121 @default.
- W2022871446 hasConcept C1998276 @default.
- W2022871446 hasConcept C2775960820 @default.
- W2022871446 hasConcept C2776953305 @default.
- W2022871446 hasConcept C2777164284 @default.
- W2022871446 hasConcept C2777495146 @default.
- W2022871446 hasConcept C2779234561 @default.
- W2022871446 hasConcept C2779742232 @default.
- W2022871446 hasConcept C2780689927 @default.
- W2022871446 hasConcept C32253518 @default.
- W2022871446 hasConcept C530470458 @default.
- W2022871446 hasConcept C54355233 @default.
- W2022871446 hasConcept C71924100 @default.
- W2022871446 hasConcept C84606932 @default.
- W2022871446 hasConcept C86803240 @default.
- W2022871446 hasConceptScore W2022871446C121608353 @default.
- W2022871446 hasConceptScore W2022871446C126322002 @default.
- W2022871446 hasConceptScore W2022871446C134018914 @default.