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- W2022872866 abstract "A combined morphologic and histochemical study of metaplastic polyps of the colorectum was undertaken. With increasing size, these lesions showed alterations in architecture and differentiation, increased secretion of carcinoembryonic antigen and a reduced secretion of O-acylated sialomucin. These functional changes are also observed in colorectal cancers, but not in tubular adenomas showing low-grade dysplasia. Since there is little clinical evidence for a metaplastic polyp-carcinoma sequence, it is suggested that the sets of factors which lead to adenoma and metaplastic polyp formation in the colorectum are both required to induce malignant transformation." @default.
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- W2022872866 date "1984-02-01" @default.
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- W2022872866 title "A morphologic and histochemical study of metaplastic polyps of the colorectum" @default.
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- W2022872866 doi "https://doi.org/10.1002/1097-0142(19840201)53:3<510::aid-cncr2820530324>3.0.co;2-o" @default.
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