FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022878856> ?p ?o ?g. }

• W2022878856 endingPage "244" @default.
• W2022878856 startingPage "238" @default.
• W2022878856 abstract "We evaluated the clinical effectiveness of variable courses of paracetamol on patent ductus arteriosus (PDA) closure and examined its effect on the in vitro term and preterm murine ductus arteriosus (DA). Neonates received one of the following three paracetamol regimens: short course of oral paracetamol (SCOP), long course of oral paracetamol (LCOP), and intravenous paracetamol (IVP) for 2–6 d. Pressure myography was used to examine changes in vasomotor tone of the preterm and term mouse DA in response to paracetamol or indomethacin. Their effect on prostaglandin synthesis by DA explants was measured by mass spectroscopy. Twenty-one preterm infants were included. No changes in PDA hemodynamics were seen in SCOP infants (n = 5). The PDA became less significant and eventually closed in six LCOP infants (n = 7). PDA closure was achieved in eight IVP infants (n = 9). On pressure myograph, paracetamol induced a concentration-dependent constriction of the term mouse DA, up to 30% of baseline (P < 0.01), but required >1 µmol/l. Indomethacin induced greater DA constriction and suppression of prostaglandin synthesis (P < 0.05). The clinical efficacy of paracetamol on PDA closure may depend on the duration of treatment and the mode of administration. Paracetamol is less potent than indomethacin for constriction of the mouse DA in vitro." @default.
• W2022878856 created "2016-06-24" @default.
• W2022878856 creator A5027196226 @default.
• W2022878856 creator A5047326291 @default.
• W2022878856 creator A5050233317 @default.
• W2022878856 creator A5061975360 @default.
• W2022878856 creator A5065172634 @default.
• W2022878856 creator A5067574356 @default.
• W2022878856 creator A5083858593 @default.
• W2022878856 creator A5085189262 @default.
• W2022878856 creator A5086937190 @default.
• W2022878856 creator A5087249715 @default.
• W2022878856 creator A5091149521 @default.
• W2022878856 date "2014-06-18" @default.
• W2022878856 modified "2023-10-18" @default.
• W2022878856 title "Efficacy of paracetamol on patent ductus arteriosus closure may be dose dependent: evidence from human and murine studies" @default.
• W2022878856 cites W1496181943 @default.
• W2022878856 cites W1969250569 @default.
• W2022878856 cites W1989084259 @default.
• W2022878856 cites W1998974649 @default.
• W2022878856 cites W2008543471 @default.
• W2022878856 cites W2020737654 @default.
• W2022878856 cites W2020971508 @default.
• W2022878856 cites W2022062040 @default.
• W2022878856 cites W2024824040 @default.
• W2022878856 cites W2054541216 @default.
• W2022878856 cites W2057755427 @default.
• W2022878856 cites W2058819195 @default.
• W2022878856 cites W2065887405 @default.
• W2022878856 cites W2068900843 @default.
• W2022878856 cites W2082584655 @default.
• W2022878856 cites W2090153487 @default.
• W2022878856 cites W2092815901 @default.
• W2022878856 cites W2105303613 @default.
• W2022878856 cites W2106221367 @default.
• W2022878856 cites W2114604788 @default.
• W2022878856 cites W2145122447 @default.
• W2022878856 cites W2163962154 @default.
• W2022878856 cites W2171485576 @default.
• W2022878856 doi "https://doi.org/10.1038/pr.2014.82" @default.
• W2022878856 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4321957" @default.
• W2022878856 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24941212" @default.
• W2022878856 hasPublicationYear "2014" @default.
• W2022878856 type Work @default.
• W2022878856 sameAs 2022878856 @default.
• W2022878856 citedByCount "62" @default.
• W2022878856 countsByYear W20228788562015 @default.
• W2022878856 countsByYear W20228788562016 @default.
• W2022878856 countsByYear W20228788562017 @default.
• W2022878856 countsByYear W20228788562018 @default.
• W2022878856 countsByYear W20228788562019 @default.
• W2022878856 countsByYear W20228788562020 @default.
• W2022878856 countsByYear W20228788562021 @default.
• W2022878856 countsByYear W20228788562022 @default.
• W2022878856 countsByYear W20228788562023 @default.
• W2022878856 crossrefType "journal-article" @default.
• W2022878856 hasAuthorship W2022878856A5027196226 @default.
• W2022878856 hasAuthorship W2022878856A5047326291 @default.
• W2022878856 hasAuthorship W2022878856A5050233317 @default.
• W2022878856 hasAuthorship W2022878856A5061975360 @default.
• W2022878856 hasAuthorship W2022878856A5065172634 @default.
• W2022878856 hasAuthorship W2022878856A5067574356 @default.
• W2022878856 hasAuthorship W2022878856A5083858593 @default.
• W2022878856 hasAuthorship W2022878856A5085189262 @default.
• W2022878856 hasAuthorship W2022878856A5086937190 @default.
• W2022878856 hasAuthorship W2022878856A5087249715 @default.
• W2022878856 hasAuthorship W2022878856A5091149521 @default.
• W2022878856 hasBestOaLocation W20228788561 @default.
• W2022878856 hasConcept C120770815 @default.
• W2022878856 hasConcept C126322002 @default.
• W2022878856 hasConcept C174940676 @default.
• W2022878856 hasConcept C178853913 @default.
• W2022878856 hasConcept C1918360 @default.
• W2022878856 hasConcept C2779941686 @default.
• W2022878856 hasConcept C2779961880 @default.
• W2022878856 hasConcept C2780664492 @default.
• W2022878856 hasConcept C2781236024 @default.
• W2022878856 hasConcept C42219234 @default.
• W2022878856 hasConcept C71924100 @default.
• W2022878856 hasConcept C98274493 @default.
• W2022878856 hasConceptScore W2022878856C120770815 @default.
• W2022878856 hasConceptScore W2022878856C126322002 @default.
• W2022878856 hasConceptScore W2022878856C174940676 @default.
• W2022878856 hasConceptScore W2022878856C178853913 @default.
• W2022878856 hasConceptScore W2022878856C1918360 @default.
• W2022878856 hasConceptScore W2022878856C2779941686 @default.
• W2022878856 hasConceptScore W2022878856C2779961880 @default.
• W2022878856 hasConceptScore W2022878856C2780664492 @default.
• W2022878856 hasConceptScore W2022878856C2781236024 @default.
• W2022878856 hasConceptScore W2022878856C42219234 @default.
• W2022878856 hasConceptScore W2022878856C71924100 @default.
• W2022878856 hasConceptScore W2022878856C98274493 @default.
• W2022878856 hasIssue "3" @default.
• W2022878856 hasLocation W20228788561 @default.
• W2022878856 hasLocation W20228788562 @default.
• W2022878856 hasLocation W20228788563 @default.
• W2022878856 hasLocation W20228788564 @default.
• W2022878856 hasOpenAccess W2022878856 @default.

• next