Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022883393> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2022883393 endingPage "23" @default.
- W2022883393 startingPage "16" @default.
- W2022883393 abstract "We have previously reported that lactating rats, unlike cycling rats, are refractory to N-methyl-D,L-aspartic acid (NMA), but not kainate, in terms of behavioral responses and activation of cFos expression in the neocortex and hippocampus. To study the factors involved in the suppression of cortical activation in lactating rats in response to NMA, we examined the effects of removing either the suckling stimulus and/or progesterone. The degree of cFos expression was used as a marker for cortical activation. Whereas control suckled animals exhibited little or no cFos activation in the piriform cortex in response to NMA, cycling rats showed a high degree of activation. Blockade of the effects of progesterone or removal of the pups for 24 h, resulted in a moderate level of cFos intensity in response to NMA. Total recovery was observed only in animals who had their pups removed for 24 h and the effects of progesterone were blocked. In general, similar results were obtained in the hippocampus except that the total recovery of hippocampal activation took longer than the cortex. Thus, the deficits in cortical activation depend on the presence of both the suckling stimulus and progesterone. However, progesterone alone cannot induce these cortical deficits since pregnant rats showed no deficits in cortical activation in response to NMA when compared to cycling rats. Therefore, the suckling stimulus is required for the inhibition of NMDA-receptor mediated activation of the cortex and hippocampus. The effects of progesterone appear to act synergistically with the effects of suckling." @default.
- W2022883393 created "2016-06-24" @default.
- W2022883393 creator A5026104880 @default.
- W2022883393 creator A5047537116 @default.
- W2022883393 creator A5084005269 @default.
- W2022883393 date "1993-02-01" @default.
- W2022883393 modified "2023-09-23" @default.
- W2022883393 title "Cortical refractoriness to N-methyl-d, l-aspartic acid (NMA) stimulation in the lactating rat: recovery after pup removal and blockade of progesterone receptors" @default.
- W2022883393 cites W1967442263 @default.
- W2022883393 cites W1972888313 @default.
- W2022883393 cites W1982210326 @default.
- W2022883393 cites W1997955014 @default.
- W2022883393 cites W2001779420 @default.
- W2022883393 cites W2002067052 @default.
- W2022883393 cites W2010132442 @default.
- W2022883393 cites W2014386083 @default.
- W2022883393 cites W2021810512 @default.
- W2022883393 cites W2021944586 @default.
- W2022883393 cites W2024822444 @default.
- W2022883393 cites W2035179009 @default.
- W2022883393 cites W2049710739 @default.
- W2022883393 cites W2060388875 @default.
- W2022883393 cites W2063900229 @default.
- W2022883393 cites W2069973923 @default.
- W2022883393 cites W2076226684 @default.
- W2022883393 cites W2083447043 @default.
- W2022883393 cites W2090981990 @default.
- W2022883393 cites W2097069565 @default.
- W2022883393 cites W2097920963 @default.
- W2022883393 cites W2107474202 @default.
- W2022883393 cites W2124706311 @default.
- W2022883393 cites W2147143888 @default.
- W2022883393 cites W2162067039 @default.
- W2022883393 doi "https://doi.org/10.1016/0006-8993(93)90347-p" @default.
- W2022883393 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8457843" @default.
- W2022883393 hasPublicationYear "1993" @default.
- W2022883393 type Work @default.
- W2022883393 sameAs 2022883393 @default.
- W2022883393 citedByCount "32" @default.
- W2022883393 countsByYear W20228833932014 @default.
- W2022883393 countsByYear W20228833932017 @default.
- W2022883393 crossrefType "journal-article" @default.
- W2022883393 hasAuthorship W2022883393A5026104880 @default.
- W2022883393 hasAuthorship W2022883393A5047537116 @default.
- W2022883393 hasAuthorship W2022883393A5084005269 @default.
- W2022883393 hasConcept C126322002 @default.
- W2022883393 hasConcept C134018914 @default.
- W2022883393 hasConcept C148762608 @default.
- W2022883393 hasConcept C170493617 @default.
- W2022883393 hasConcept C185592680 @default.
- W2022883393 hasConcept C24998067 @default.
- W2022883393 hasConcept C2778468042 @default.
- W2022883393 hasConcept C2780382662 @default.
- W2022883393 hasConcept C2781161787 @default.
- W2022883393 hasConcept C67018056 @default.
- W2022883393 hasConcept C71924100 @default.
- W2022883393 hasConceptScore W2022883393C126322002 @default.
- W2022883393 hasConceptScore W2022883393C134018914 @default.
- W2022883393 hasConceptScore W2022883393C148762608 @default.
- W2022883393 hasConceptScore W2022883393C170493617 @default.
- W2022883393 hasConceptScore W2022883393C185592680 @default.
- W2022883393 hasConceptScore W2022883393C24998067 @default.
- W2022883393 hasConceptScore W2022883393C2778468042 @default.
- W2022883393 hasConceptScore W2022883393C2780382662 @default.
- W2022883393 hasConceptScore W2022883393C2781161787 @default.
- W2022883393 hasConceptScore W2022883393C67018056 @default.
- W2022883393 hasConceptScore W2022883393C71924100 @default.
- W2022883393 hasIssue "1-2" @default.
- W2022883393 hasLocation W20228833931 @default.
- W2022883393 hasLocation W20228833932 @default.
- W2022883393 hasOpenAccess W2022883393 @default.
- W2022883393 hasPrimaryLocation W20228833931 @default.
- W2022883393 hasRelatedWork W1984619393 @default.
- W2022883393 hasRelatedWork W2019185608 @default.
- W2022883393 hasRelatedWork W2032433134 @default.
- W2022883393 hasRelatedWork W2034583712 @default.
- W2022883393 hasRelatedWork W2034768996 @default.
- W2022883393 hasRelatedWork W2044141036 @default.
- W2022883393 hasRelatedWork W2054992011 @default.
- W2022883393 hasRelatedWork W2063619316 @default.
- W2022883393 hasRelatedWork W2064416809 @default.
- W2022883393 hasRelatedWork W2096633132 @default.
- W2022883393 hasVolume "604" @default.
- W2022883393 isParatext "false" @default.
- W2022883393 isRetracted "false" @default.
- W2022883393 magId "2022883393" @default.
- W2022883393 workType "article" @default.