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• W2022885287 abstract "The need for a potent HIV protease inhibitor (PI) to combat emerging PI-resistant viruses is anticipated. Analogs formulated from the combination of structural fragments of Ritonavir, Lopinavir, and Amprenavir were synthesized. Analogs containing the oxime pharmacophore were found to have improved activities against both wild type and resistant (A17) viruses. The synthesis and structure–activity relationships (SAR) based upon the in vitro IC50 of this series of compounds are reported." @default.
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• W2022885287 date "2005-05-01" @default.
• W2022885287 modified "2023-09-23" @default.
• W2022885287 title "Oximinoarylsulfonamides as potent HIV protease inhibitors" @default.
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• W2022885287 doi "https://doi.org/10.1016/j.bmcl.2005.03.008" @default.
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