FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022887896> ?p ?o ?g. }

• W2022887896 abstract "HIV-infected women, particularly those with advanced disease, may have higher rates of pregnancy loss (miscarriage and stillbirth) and neonatal mortality than uninfected women. Here we examine risk factors for these adverse pregnancy outcomes in a cohort of HIV-infected women in Zambia considering the impact of infant HIV status.A total of 1229 HIV-infected pregnant women were enrolled (2001-2004) in Lusaka, Zambia and followed to pregnancy outcome. Live-born infants were tested for HIV by PCR at birth, 1 week and 5 weeks. Obstetric and neonatal data were collected after delivery and the rates of neonatal (<28 days) and early mortality (<70 days) were described using Kaplan-Meier methods.The ratio of miscarriage and stillbirth per 100 live-births were 3.1 and 2.6, respectively. Higher maternal plasma viral load (adjusted odds ratio [AOR] for each log10 increase in HIV RNA copies/ml = 1.90; 95% confidence interval [CI] 1.10-3.27) and being symptomatic were associated with an increased risk of stillbirth (AOR = 3.19; 95% CI 1.46-6.97), and decreasing maternal CD4 count by 100 cells/mm3 with an increased risk of miscarriage (OR = 1.25; 95% CI 1.02-1.54). The neonatal mortality rate was 4.3 per 100 increasing to 6.3 by 70 days. Intrauterine HIV infection was not associated with neonatal morality but became associated with mortality through 70 days (adjusted hazard ratio = 2.76; 95% CI 1.25-6.08). Low birth weight and cessation of breastfeeding were significant risk factors for both neonatal and early mortality independent of infant HIV infection.More advanced maternal HIV disease was associated with adverse pregnancy outcomes. Excess neonatal mortality in HIV-infected women was not primarily explained by infant HIV infection but was strongly associated with low birth weight and prematurity. Intrauterine HIV infection contributed to mortality as early as 70 days of infant age. Interventions to improve pregnancy outcomes for HIV-infected women are needed to complement necessary therapeutic and prophylactic antiretroviral interventions." @default.
• W2022887896 created "2016-06-24" @default.
• W2022887896 creator A5023011193 @default.
• W2022887896 creator A5039928708 @default.
• W2022887896 creator A5052608832 @default.
• W2022887896 creator A5055401131 @default.
• W2022887896 creator A5061807892 @default.
• W2022887896 creator A5065078265 @default.
• W2022887896 creator A5073718294 @default.
• W2022887896 creator A5078059377 @default.
• W2022887896 date "2012-08-31" @default.
• W2022887896 modified "2023-10-06" @default.
• W2022887896 title "Pregnancy loss and role of infant HIV status on perinatal mortality among HIV-infected women" @default.
• W2022887896 cites W1840248980 @default.
• W2022887896 cites W1964867999 @default.
• W2022887896 cites W1972790667 @default.
• W2022887896 cites W1974229364 @default.
• W2022887896 cites W1978202493 @default.
• W2022887896 cites W1980453489 @default.
• W2022887896 cites W1986043432 @default.
• W2022887896 cites W1994669505 @default.
• W2022887896 cites W1997560305 @default.
• W2022887896 cites W2005732333 @default.
• W2022887896 cites W2008412906 @default.
• W2022887896 cites W2014651948 @default.
• W2022887896 cites W2016738212 @default.
• W2022887896 cites W2017442023 @default.
• W2022887896 cites W2021430036 @default.
• W2022887896 cites W2029781766 @default.
• W2022887896 cites W2047997080 @default.
• W2022887896 cites W2054012799 @default.
• W2022887896 cites W2064499675 @default.
• W2022887896 cites W2077557752 @default.
• W2022887896 cites W2077748901 @default.
• W2022887896 cites W2079324608 @default.
• W2022887896 cites W2084974206 @default.
• W2022887896 cites W2089034023 @default.
• W2022887896 cites W2090432953 @default.
• W2022887896 cites W2093560165 @default.
• W2022887896 cites W2114707498 @default.
• W2022887896 cites W2116914456 @default.
• W2022887896 cites W2122986037 @default.
• W2022887896 cites W2124263262 @default.
• W2022887896 cites W2126908000 @default.
• W2022887896 cites W2129989508 @default.
• W2022887896 cites W2143162438 @default.
• W2022887896 cites W2146891171 @default.
• W2022887896 cites W2148521133 @default.
• W2022887896 cites W2150250267 @default.
• W2022887896 cites W2150760916 @default.
• W2022887896 cites W2151167734 @default.
• W2022887896 cites W2154863356 @default.
• W2022887896 cites W2160051704 @default.
• W2022887896 cites W2164241626 @default.
• W2022887896 cites W2164723930 @default.
• W2022887896 cites W2312499014 @default.
• W2022887896 cites W2313126192 @default.
• W2022887896 cites W2331780577 @default.
• W2022887896 cites W4232318562 @default.
• W2022887896 cites W4245472523 @default.
• W2022887896 cites W4247239092 @default.
• W2022887896 cites W4382312230 @default.
• W2022887896 doi "https://doi.org/10.1186/1471-2431-12-138" @default.
• W2022887896 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3480840" @default.
• W2022887896 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22937874" @default.
• W2022887896 hasPublicationYear "2012" @default.
• W2022887896 type Work @default.
• W2022887896 sameAs 2022887896 @default.
• W2022887896 citedByCount "54" @default.
• W2022887896 countsByYear W20228878962013 @default.
• W2022887896 countsByYear W20228878962014 @default.
• W2022887896 countsByYear W20228878962015 @default.
• W2022887896 countsByYear W20228878962016 @default.
• W2022887896 countsByYear W20228878962017 @default.
• W2022887896 countsByYear W20228878962018 @default.
• W2022887896 countsByYear W20228878962019 @default.
• W2022887896 countsByYear W20228878962020 @default.
• W2022887896 countsByYear W20228878962021 @default.
• W2022887896 countsByYear W20228878962022 @default.
• W2022887896 countsByYear W20228878962023 @default.
• W2022887896 crossrefType "journal-article" @default.
• W2022887896 hasAuthorship W2022887896A5023011193 @default.
• W2022887896 hasAuthorship W2022887896A5039928708 @default.
• W2022887896 hasAuthorship W2022887896A5052608832 @default.
• W2022887896 hasAuthorship W2022887896A5055401131 @default.
• W2022887896 hasAuthorship W2022887896A5061807892 @default.
• W2022887896 hasAuthorship W2022887896A5065078265 @default.
• W2022887896 hasAuthorship W2022887896A5073718294 @default.
• W2022887896 hasAuthorship W2022887896A5078059377 @default.
• W2022887896 hasBestOaLocation W20228878961 @default.
• W2022887896 hasConcept C126322002 @default.
• W2022887896 hasConcept C131872663 @default.
• W2022887896 hasConcept C142462285 @default.
• W2022887896 hasConcept C156957248 @default.
• W2022887896 hasConcept C187212893 @default.
• W2022887896 hasConcept C201903717 @default.
• W2022887896 hasConcept C203014093 @default.
• W2022887896 hasConcept C207103383 @default.
• W2022887896 hasConcept C2776283161 @default.
• W2022887896 hasConcept C2779083892 @default.

• next