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• W2022889787 abstract "We investigated whether the psychostimulant methamphetamine (METH) has a cytotoxic effect on oligodendrocytes and which cell-death pathways are involved in the cytotoxic process. METH caused concentration- and time-dependent cytotoxicity in rat oligodendrocyte cultures. METH induced apoptotic cell death and mRNA expression of pro-apoptotic proteins (bax and DP5), but not anti-apoptotic proteins (bcl-2 and bcl-XL). These results suggest that METH induces cytotoxicity in rat oligodendrocytes via the differential regulation of the expression of genes involved in the apoptotic process." @default.
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• W2022889787 date "2003-08-01" @default.
• W2022889787 modified "2023-09-24" @default.
• W2022889787 title "Methamphetamine induces oligodendroglial cell death in vitro" @default.
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• W2022889787 doi "https://doi.org/10.1016/s0006-8993(03)02890-7" @default.
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