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• W2022892895 startingPage "59" @default.
• W2022892895 abstract "To compare the susceptibility of early life stages (ELS) of rainbow trout (Salmo gairdneri), acute toxicity studies were carried out with cadmium, maneb, pentachlorophenol, 1,2,4,5-tetrachlorobenzene, parathion and dieldrin. The tests were performed with fertilized eggs before and after water hardening, early eye point eggs, late eye point eggs, sac fry and early fry. In all cases the early fry stage appeared the most critical period. Additionally, short-term static bioaccumulation experiments were performed with [14C]dieldrin. A kinetic model was developed for the static accumulation studies. The bioconcentration factor increased during embryonic development, reached a maximum at the sac fry stage and fell off again at the early fry stage. The uptake rate constant clearly increased once the egg membrane had disappeared and reached its maximum at the early fry stage. The clearance rate constant sharply increased at the early fry stage. Dieldrin was recovered almost completely from the yolk, which acted as a temporary ‘toxicant sink’. Changes in the susceptibility of ELS of S. gairdneri to pollutants are explained by metabolic modifications during embryolarval development and only partly by differences in the accessibility of the toxicants. In conclusion it is stated that in view of the lack of fish toxicity data, short-term exposure of early fry is a practical approximation in establishing toxicant concentrations acceptable for fish. For compounds having a high bioaccumulative potential the exposure period should also include the sac fry stage." @default.
• W2022892895 created "2016-06-24" @default.
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• W2022892895 date "1985-10-01" @default.
• W2022892895 modified "2023-10-09" @default.
• W2022892895 title "Differences in susceptibility of early life stages of rainbow trout (Salmo gairdneri) to environmental pollutants" @default.
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• W2022892895 doi "https://doi.org/10.1016/0166-445x(85)90036-0" @default.
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