Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022897315> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2022897315 endingPage "1187" @default.
- W2022897315 startingPage "1179" @default.
- W2022897315 abstract "Individuals of blood group O and nonsecretors of ABO blood group antigens are more susceptible to peptic ulcers. The aim of this study was to determine if blood group antigens associated with group O or secretor status are epithelial cell receptors for Helicobacter pylori.Bacterial binding and binding of monoclonal antibodies to H type 2, Lewis(a), and Lewis(b) to Kato III, buccal epithelial, and gastric mucosal cells were shown by flow cytometry. Bacterial outer membrane proteins eluted from H type 2, Lewis(a), or Lewis(b) were shown by polyacrylamide gel electrophoresis.Kato III and human epithelial cells bound each monoclonal antibody; O cells bound more anti-H type 2 (P < 0.05). Binding indices for H. pylori correlated with those for anti-H type 2 (P < 0.005) and anti-Lewis(b) (P < 0.001) but not anti-Lewis(a). A 61-kilodalton protein was eluted from H type 2, Lewis(a), or Lewis(b).Our results indicate that H type 2 is an important receptor for the 61-kilodalton bacterial adhesin, partly explaining increased susceptibility of individuals of blood group O to ulcers. Lewis(b) binds H. pylori more efficiently than Lewis(a). If these interactions occur in vivo, lack of Lewis(b) in mucosal fluids of nonsecretors may contribute to colonization by H. pylori." @default.
- W2022897315 created "2016-06-24" @default.
- W2022897315 creator A5014044923 @default.
- W2022897315 creator A5023333493 @default.
- W2022897315 creator A5027852010 @default.
- W2022897315 creator A5031769231 @default.
- W2022897315 creator A5062456952 @default.
- W2022897315 creator A5062888526 @default.
- W2022897315 creator A5076461766 @default.
- W2022897315 date "1997-04-01" @default.
- W2022897315 modified "2023-09-27" @default.
- W2022897315 title "Isolation of a cell surface component of Helicobacter pylori that binds H type 2, Lewis(a), and Lewis(b) antigens" @default.
- W2022897315 cites W1853727284 @default.
- W2022897315 cites W2030336958 @default.
- W2022897315 doi "https://doi.org/10.1016/s0016-5085(97)70129-x" @default.
- W2022897315 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9098001" @default.
- W2022897315 hasPublicationYear "1997" @default.
- W2022897315 type Work @default.
- W2022897315 sameAs 2022897315 @default.
- W2022897315 citedByCount "76" @default.
- W2022897315 countsByYear W20228973152013 @default.
- W2022897315 countsByYear W20228973152014 @default.
- W2022897315 countsByYear W20228973152015 @default.
- W2022897315 countsByYear W20228973152016 @default.
- W2022897315 countsByYear W20228973152017 @default.
- W2022897315 countsByYear W20228973152018 @default.
- W2022897315 countsByYear W20228973152019 @default.
- W2022897315 countsByYear W20228973152020 @default.
- W2022897315 countsByYear W20228973152022 @default.
- W2022897315 countsByYear W20228973152023 @default.
- W2022897315 crossrefType "journal-article" @default.
- W2022897315 hasAuthorship W2022897315A5014044923 @default.
- W2022897315 hasAuthorship W2022897315A5023333493 @default.
- W2022897315 hasAuthorship W2022897315A5027852010 @default.
- W2022897315 hasAuthorship W2022897315A5031769231 @default.
- W2022897315 hasAuthorship W2022897315A5062456952 @default.
- W2022897315 hasAuthorship W2022897315A5062888526 @default.
- W2022897315 hasAuthorship W2022897315A5076461766 @default.
- W2022897315 hasConcept C104317684 @default.
- W2022897315 hasConcept C147483822 @default.
- W2022897315 hasConcept C153911025 @default.
- W2022897315 hasConcept C159654299 @default.
- W2022897315 hasConcept C176080213 @default.
- W2022897315 hasConcept C179470777 @default.
- W2022897315 hasConcept C185592680 @default.
- W2022897315 hasConcept C203014093 @default.
- W2022897315 hasConcept C2776409635 @default.
- W2022897315 hasConcept C542903549 @default.
- W2022897315 hasConcept C54355233 @default.
- W2022897315 hasConcept C547475151 @default.
- W2022897315 hasConcept C553184892 @default.
- W2022897315 hasConcept C55493867 @default.
- W2022897315 hasConcept C86803240 @default.
- W2022897315 hasConcept C89423630 @default.
- W2022897315 hasConceptScore W2022897315C104317684 @default.
- W2022897315 hasConceptScore W2022897315C147483822 @default.
- W2022897315 hasConceptScore W2022897315C153911025 @default.
- W2022897315 hasConceptScore W2022897315C159654299 @default.
- W2022897315 hasConceptScore W2022897315C176080213 @default.
- W2022897315 hasConceptScore W2022897315C179470777 @default.
- W2022897315 hasConceptScore W2022897315C185592680 @default.
- W2022897315 hasConceptScore W2022897315C203014093 @default.
- W2022897315 hasConceptScore W2022897315C2776409635 @default.
- W2022897315 hasConceptScore W2022897315C542903549 @default.
- W2022897315 hasConceptScore W2022897315C54355233 @default.
- W2022897315 hasConceptScore W2022897315C547475151 @default.
- W2022897315 hasConceptScore W2022897315C553184892 @default.
- W2022897315 hasConceptScore W2022897315C55493867 @default.
- W2022897315 hasConceptScore W2022897315C86803240 @default.
- W2022897315 hasConceptScore W2022897315C89423630 @default.
- W2022897315 hasIssue "4" @default.
- W2022897315 hasLocation W20228973151 @default.
- W2022897315 hasLocation W20228973152 @default.
- W2022897315 hasOpenAccess W2022897315 @default.
- W2022897315 hasPrimaryLocation W20228973151 @default.
- W2022897315 hasRelatedWork W1997716688 @default.
- W2022897315 hasRelatedWork W2038126255 @default.
- W2022897315 hasRelatedWork W2064089409 @default.
- W2022897315 hasRelatedWork W2068190618 @default.
- W2022897315 hasRelatedWork W2087041936 @default.
- W2022897315 hasRelatedWork W2150089197 @default.
- W2022897315 hasRelatedWork W2368460920 @default.
- W2022897315 hasRelatedWork W2380360044 @default.
- W2022897315 hasRelatedWork W36359752 @default.
- W2022897315 hasRelatedWork W167744410 @default.
- W2022897315 hasVolume "112" @default.
- W2022897315 isParatext "false" @default.
- W2022897315 isRetracted "false" @default.
- W2022897315 magId "2022897315" @default.
- W2022897315 workType "article" @default.