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- W2022897534 abstract "Three of 35 U.S. children (<18 years old) with AIDS reported to the Centers for Disease Control (CDC) as of December 1983 had hemophilia. We summarize these and 2 European pediatric AIDS patients with hemophilia, reported to CDC. All 5 patients were white and male; ages ranged from 9-16 years. Four patients had severe hemophilia A; 1, moderate hemophilia B. Two cases resided in New York; 1, in Pennsylvania; the European cases were Spanish and siblings. Four patients presented with fever and weight loss; all had pulmonary symptoms. All cases had laboratory findings consistent with AIDS and had opportunistic infections (OI) including Pneumocystis carinii pneumonia, systemic cytomegalovirus, and systemic fungal infections. Three patients (60%) have died. None had other known risk factors for AIDS or immunosuppressive therapy. The hemophilia B patient received 2 units of whole blood in 1982 and no other blood products. Factor VIII was the only blood product received by both U.S. hemophilia A patients in the past 5 years. The prevalence of hemophilia in pediatric AIDS patients is much higher than its estimated population prevalence (1 in 10,000), indicating that hemophilia is a risk factor for AIDS. AIDS may occur in those receiving only factor or only whole blood therapy. Pediatricians should consider AIDS in any patient with hemophilia and unexplained weight loss, fever, or OI. To help further clarify the role of blood products in AIDS transmission, they should inquire about all product usage and other AIDS risk factors." @default.
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- W2022897534 date "1984-04-01" @default.
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- W2022897534 title "ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS) IN PEDIATRIC HEMOPHILIACS" @default.
- W2022897534 doi "https://doi.org/10.1203/00006450-198404001-01112" @default.
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