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- W2022911069 abstract "Reports from the past year increased the database for comparison of pancreatic carcinomas in animal models and in humans. Mutation of the c-K-ras oncogene, present in a high fraction of human cancers, was found in hamster but not in rat pancreatic, carcinomas and extends similarities of hamster and human tumors to the oncogene level. Expression of transforming growth factor-a, demonstrated in several human pancreatic carcinomas, was not sufficient to cause carcinoma in the pancreas of transgenic mice, but was associated with pancreatic fibrosis, a feature of many human cancers. New studies strengthen the basis for clinical trials of hormonal therapy in pancreatic cancer, but suggest that efforts should be made to identify prospectively those patients who will respond to such treatment." @default.
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- W2022911069 title "Experimental cancer of the pancreas" @default.
- W2022911069 doi "https://doi.org/10.1097/00001574-199110000-00008" @default.
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