FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022923181> ?p ?o ?g. }

• W2022923181 endingPage "21996" @default.
• W2022923181 startingPage "21989" @default.
• W2022923181 abstract "The effects of salt on the intermolecular interactions between polar/charged amino acids are investigated through molecular dynamics simulations. The mean forces and associated potentials are calculated for NaCl salt in the 0−2 M concentration range at 298 K. It is found that the addition of salt may stabilize or destabilize the interactions, depending on the nature of the interacting molecules. The degree of (de)stabilization is quantified, and the origin of the salt-dependent modulation is discussed based upon an analysis of solvent density profiles. To gain insight into the molecular origin of the salt modulation, spatial distribution functions (sdf's) are calculated, revealing a high degree of solvent structuredness in all cases. The peaks in the sdf's are consistent with long-range hydrogen-bonding networks connecting the solute hydrophilic groups, and that contribute to their intermolecular solvent-induced forces. The restructuring of water around the solutes as they dissociate from close contact is analyzed. This analysis offers clues on how the solvent structure modulates the effective intermolecular interactions in complex solutes. This modulation results from a critical balance between bulk electrostatic forces and those exerted by (i) the water molecules in the structured region between the monomers, which is disrupted by ions that transiently enter the hydration shells, and (ii) the ions in the hydration shells in direct interactions with the solutes. The implications of these findings in protein/ligand (noncovalent) association/dissociation mechanisms are briefly discussed." @default.
• W2022923181 created "2016-06-24" @default.
• W2022923181 creator A5091353022 @default.
• W2022923181 date "2005-10-28" @default.
• W2022923181 modified "2023-10-10" @default.
• W2022923181 title "Amino Acid Side Chain Interactions in the Presence of Salts" @default.
• W2022923181 cites W1494326194 @default.
• W2022923181 cites W1498235692 @default.
• W2022923181 cites W1517953913 @default.
• W2022923181 cites W1534963014 @default.
• W2022923181 cites W1572013437 @default.
• W2022923181 cites W176210329 @default.
• W2022923181 cites W1966020703 @default.
• W2022923181 cites W1981624793 @default.
• W2022923181 cites W1984498082 @default.
• W2022923181 cites W1990759970 @default.
• W2022923181 cites W1991017182 @default.
• W2022923181 cites W1991587990 @default.
• W2022923181 cites W1997151511 @default.
• W2022923181 cites W1998790318 @default.
• W2022923181 cites W2000702472 @default.
• W2022923181 cites W2003003096 @default.
• W2022923181 cites W2005679019 @default.
• W2022923181 cites W2013308479 @default.
• W2022923181 cites W2017417570 @default.
• W2022923181 cites W2025333274 @default.
• W2022923181 cites W2043724966 @default.
• W2022923181 cites W2046889151 @default.
• W2022923181 cites W2049132731 @default.
• W2022923181 cites W2049991944 @default.
• W2022923181 cites W2053246876 @default.
• W2022923181 cites W2055048415 @default.
• W2022923181 cites W2057155675 @default.
• W2022923181 cites W2064969595 @default.
• W2022923181 cites W2080563488 @default.
• W2022923181 cites W2082136648 @default.
• W2022923181 cites W2082840184 @default.
• W2022923181 cites W2083308932 @default.
• W2022923181 cites W2085322299 @default.
• W2022923181 cites W2086288291 @default.
• W2022923181 cites W2086295275 @default.
• W2022923181 cites W2088908206 @default.
• W2022923181 cites W2090756656 @default.
• W2022923181 cites W2093221728 @default.
• W2022923181 cites W2096921126 @default.
• W2022923181 cites W2108453057 @default.
• W2022923181 cites W2113307443 @default.
• W2022923181 cites W2127883090 @default.
• W2022923181 cites W2131754023 @default.
• W2022923181 cites W2135176361 @default.
• W2022923181 cites W2135964386 @default.
• W2022923181 cites W2158801277 @default.
• W2022923181 cites W2162166182 @default.
• W2022923181 cites W2169429313 @default.
• W2022923181 cites W2171678638 @default.
• W2022923181 cites W2412601725 @default.
• W2022923181 cites W3102934655 @default.
• W2022923181 doi "https://doi.org/10.1021/jp054042r" @default.
• W2022923181 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1366496" @default.
• W2022923181 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16479276" @default.
• W2022923181 hasPublicationYear "2005" @default.
• W2022923181 type Work @default.
• W2022923181 sameAs 2022923181 @default.
• W2022923181 citedByCount "40" @default.
• W2022923181 countsByYear W20229231812012 @default.
• W2022923181 countsByYear W20229231812013 @default.
• W2022923181 countsByYear W20229231812014 @default.
• W2022923181 countsByYear W20229231812015 @default.
• W2022923181 countsByYear W20229231812016 @default.
• W2022923181 countsByYear W20229231812017 @default.
• W2022923181 countsByYear W20229231812018 @default.
• W2022923181 countsByYear W20229231812019 @default.
• W2022923181 countsByYear W20229231812021 @default.
• W2022923181 countsByYear W20229231812022 @default.
• W2022923181 countsByYear W20229231812023 @default.
• W2022923181 crossrefType "journal-article" @default.
• W2022923181 hasAuthorship W2022923181A5091353022 @default.
• W2022923181 hasBestOaLocation W20229231812 @default.
• W2022923181 hasConcept C102931765 @default.
• W2022923181 hasConcept C112887158 @default.
• W2022923181 hasConcept C137277065 @default.
• W2022923181 hasConcept C145148216 @default.
• W2022923181 hasConcept C147597530 @default.
• W2022923181 hasConcept C147789679 @default.
• W2022923181 hasConcept C148093993 @default.
• W2022923181 hasConcept C159467904 @default.
• W2022923181 hasConcept C166940927 @default.
• W2022923181 hasConcept C166950319 @default.
• W2022923181 hasConcept C178790620 @default.
• W2022923181 hasConcept C185592680 @default.
• W2022923181 hasConcept C204921945 @default.
• W2022923181 hasConcept C2776371256 @default.
• W2022923181 hasConcept C2780471494 @default.
• W2022923181 hasConcept C32909587 @default.
• W2022923181 hasConcept C521977710 @default.
• W2022923181 hasConcept C59593255 @default.
• W2022923181 hasConcept C8010536 @default.
• W2022923181 hasConcept C90260826 @default.

• next