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• W2022931549 startingPage "1924" @default.
• W2022931549 abstract "The effects of hypoxia on release of endogenous 3,4-dihydroxyphenylethylamine (DA, dopamine) were investigated in mouse striatal slices. Following a 60-min preincubation, potassium increased DA release 12 times between zero and 1 min. By 10 min, uptake processes exceeded release and DA levels in the media decreased. Hypoxia (low oxygen) and anoxia (no oxygen) increased DA in the media by 120 and 205%, respectively, but did not alter dihydroxyphenylacetic acid concentrations. Under similar conditions, anoxia increased [3H]DA uptake eight-fold. For the uptake studies, the amount of DA added to the media was critical; in the presence of high concentrations of DA, anoxia reduced reuptake. Regardless of exogenous DA, hypoxia and anoxia increased extracellular DA, which may play a role in ischemic cell damage." @default.
• W2022931549 created "2016-06-24" @default.
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• W2022931549 date "1986-12-01" @default.
• W2022931549 modified "2023-10-16" @default.
• W2022931549 title "Effect of Decreased Oxygen on In Vitro Release of Endogenous 3,4-Dihydroxyphenylethylamine from Mouse Striatum" @default.
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• W2022931549 doi "https://doi.org/10.1111/j.1471-4159.1986.tb13109.x" @default.
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