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- W2022931805 abstract "Water transport across the blood-brain barrier was studied in 15 patients during hypertonic intracarotid injection. The filtration permeability coefficient (Pf) measured in 10 patients was 10.4 × 10−4 cm sec−1. The diffusion permeability coefficient (Pd) for tracer water measured in 12 patients was 2.4 × 10−4 cm sec−1, but this value is probably too small due to back diffusion. The PfPd ratio was 4.3 and might therefore be even smaller. The results indicate that pores or slits are not present in the blood-brain barrier and probably all water transport occurs by dissolving in the membrane phase." @default.
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- W2022931805 date "1977-01-01" @default.
- W2022931805 modified "2023-10-12" @default.
- W2022931805 title "Filtration and diffusion of water across the blood-brain barrier in man" @default.
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- W2022931805 doi "https://doi.org/10.1016/0026-2862(77)90120-0" @default.
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