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- W2022940523 abstract "A continuous decline in immune responses to Newcastle disease (ND) vaccine was observed in commercial broiler flocks in Croatia, Slovenia, and Bosnia and Herzegovina beginning in 1982. Floating mean haemagglutination inhibition (HI) titres declined from log2 4 in 1983 to a low of log2 2.4 in 1986, then were log2 2.9 in 1990. Several causes of the decline were discounted, leaving mycotoxins in feed and infection with chicken anaemia virus (CAV) as the two most likely causes. Mycotoxins in feed could not be evaluated retrospectively, but archival tissues were available from Croatia and Slovenia. Tissue sections were examined by in situ hybridization for CAV. Whereas only one chicken from early in the decade was infected, all but one of the chickens from late in the decade were. The increase in CAV detection correlated inversely with ND HI titres. Whereas this correlation does not establish cause and effect, CAV cannot be eliminated as a contributory cause of immune suppression." @default.
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- W2022940523 date "1998-04-01" @default.
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- W2022940523 title "Immune suppression of commercial broilers in Croatia, Slovenia, and Bosnia and Herzegovina from 1981 to 1991" @default.
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- W2022940523 doi "https://doi.org/10.1080/03079459808419324" @default.
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