FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022947570> ?p ?o ?g. }

• W2022947570 endingPage "1129" @default.
• W2022947570 startingPage "1124" @default.
• W2022947570 abstract "The objective of this study is to evaluate the effect and mechanism of mitochondria-targeted peptides (MTP131 and SPI20) on contrast-induced acute kidney injury (CI-AKI) in rats with hypercholesterolemia.Forty SD rats were randomly divided into normal diet group (NN, n = 8) and high cholesterol supplemented dietary group (HN, n = 32). At the end of 8 weeks, the group HN was divided into four subgroups. All Rats were given injection of either diatrizoate (10 mL/kg) or equal volume of normal saline, the rats pretreated with MTP131 or SPI20 were given injection with MTP131 or SPI 20 (3 mg/kg) by peritoneal cavity for 3 times. Blood, urine and renal tissue samples were prepared to determine biochemical parameters. The renal pathological changes were evaluated by hematoxylin and eosin staining and scored semiquantitatively, The protein expression of renal NOX4 was also measured by Western blotting.In diatrizoate-injected rats, Serum creatinine (Scr), fractional excretion of sodium (FeNa%), fractional excretion of potassium (FeK%), pathological scores, renal malondialdehyde (MDA) content, the NADPH oxidase activity and the expression of NOX4 in kidney tissue were significantly increased (p < 0.01). In the groups pretreated with MTP131 or SPI20, the levels of Scr, FeNa%, FeK%, MDA content and NADPH oxidase activity in renal tissue decreased (p < 0.01), the levels of renal super oxygen dehydrogenises and ATPase activity increased (p < 0.01). The renal injuries induced by contrast media (CM) were alleviated.MTP131 and SPI20 might protect acute kidney injury induced by CM in rats with hypercholesterolemia." @default.
• W2022947570 created "2016-06-24" @default.
• W2022947570 creator A5007565264 @default.
• W2022947570 creator A5031271574 @default.
• W2022947570 creator A5035492954 @default.
• W2022947570 creator A5049781553 @default.
• W2022947570 creator A5053518219 @default.
• W2022947570 creator A5079809915 @default.
• W2022947570 creator A5085025467 @default.
• W2022947570 date "2013-07-23" @default.
• W2022947570 modified "2023-10-18" @default.
• W2022947570 title "Mitochondria-targeted peptides prevent on contrast-induced acute kidney injury in the rats with hypercholesterolemia" @default.
• W2022947570 cites W1973205178 @default.
• W2022947570 cites W1975117868 @default.
• W2022947570 cites W1975785349 @default.
• W2022947570 cites W1988723465 @default.
• W2022947570 cites W1991728780 @default.
• W2022947570 cites W1998368140 @default.
• W2022947570 cites W2003500862 @default.
• W2022947570 cites W2033637369 @default.
• W2022947570 cites W2055456981 @default.
• W2022947570 cites W2057076974 @default.
• W2022947570 cites W2058597255 @default.
• W2022947570 cites W2061514693 @default.
• W2022947570 cites W2079349521 @default.
• W2022947570 cites W2080563483 @default.
• W2022947570 cites W2085128107 @default.
• W2022947570 cites W2091918640 @default.
• W2022947570 cites W2119301730 @default.
• W2022947570 cites W2120180111 @default.
• W2022947570 cites W2132347872 @default.
• W2022947570 cites W2143138797 @default.
• W2022947570 cites W2143750325 @default.
• W2022947570 cites W2159285342 @default.
• W2022947570 doi "https://doi.org/10.3109/0886022x.2013.815107" @default.
• W2022947570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23879473" @default.
• W2022947570 hasPublicationYear "2013" @default.
• W2022947570 type Work @default.
• W2022947570 sameAs 2022947570 @default.
• W2022947570 citedByCount "19" @default.
• W2022947570 countsByYear W20229475702014 @default.
• W2022947570 countsByYear W20229475702015 @default.
• W2022947570 countsByYear W20229475702016 @default.
• W2022947570 countsByYear W20229475702017 @default.
• W2022947570 countsByYear W20229475702018 @default.
• W2022947570 countsByYear W20229475702019 @default.
• W2022947570 countsByYear W20229475702020 @default.
• W2022947570 countsByYear W20229475702022 @default.
• W2022947570 countsByYear W20229475702023 @default.
• W2022947570 crossrefType "journal-article" @default.
• W2022947570 hasAuthorship W2022947570A5007565264 @default.
• W2022947570 hasAuthorship W2022947570A5031271574 @default.
• W2022947570 hasAuthorship W2022947570A5035492954 @default.
• W2022947570 hasAuthorship W2022947570A5049781553 @default.
• W2022947570 hasAuthorship W2022947570A5053518219 @default.
• W2022947570 hasAuthorship W2022947570A5079809915 @default.
• W2022947570 hasAuthorship W2022947570A5085025467 @default.
• W2022947570 hasBestOaLocation W20229475701 @default.
• W2022947570 hasConcept C10146269 @default.
• W2022947570 hasConcept C126322002 @default.
• W2022947570 hasConcept C134018914 @default.
• W2022947570 hasConcept C2776151105 @default.
• W2022947570 hasConcept C2778401633 @default.
• W2022947570 hasConcept C2779719074 @default.
• W2022947570 hasConcept C2779765511 @default.
• W2022947570 hasConcept C2780091579 @default.
• W2022947570 hasConcept C2780306776 @default.
• W2022947570 hasConcept C2780343553 @default.
• W2022947570 hasConcept C2780472472 @default.
• W2022947570 hasConcept C71924100 @default.
• W2022947570 hasConceptScore W2022947570C10146269 @default.
• W2022947570 hasConceptScore W2022947570C126322002 @default.
• W2022947570 hasConceptScore W2022947570C134018914 @default.
• W2022947570 hasConceptScore W2022947570C2776151105 @default.
• W2022947570 hasConceptScore W2022947570C2778401633 @default.
• W2022947570 hasConceptScore W2022947570C2779719074 @default.
• W2022947570 hasConceptScore W2022947570C2779765511 @default.
• W2022947570 hasConceptScore W2022947570C2780091579 @default.
• W2022947570 hasConceptScore W2022947570C2780306776 @default.
• W2022947570 hasConceptScore W2022947570C2780343553 @default.
• W2022947570 hasConceptScore W2022947570C2780472472 @default.
• W2022947570 hasConceptScore W2022947570C71924100 @default.
• W2022947570 hasIssue "8" @default.
• W2022947570 hasLocation W20229475701 @default.
• W2022947570 hasLocation W20229475702 @default.
• W2022947570 hasOpenAccess W2022947570 @default.
• W2022947570 hasPrimaryLocation W20229475701 @default.
• W2022947570 hasRelatedWork W1496672822 @default.
• W2022947570 hasRelatedWork W2078018645 @default.
• W2022947570 hasRelatedWork W2106189792 @default.
• W2022947570 hasRelatedWork W2117261670 @default.
• W2022947570 hasRelatedWork W2165953544 @default.
• W2022947570 hasRelatedWork W2170266244 @default.
• W2022947570 hasRelatedWork W2808833115 @default.
• W2022947570 hasRelatedWork W3032584988 @default.
• W2022947570 hasRelatedWork W3176234867 @default.
• W2022947570 hasRelatedWork W820032666 @default.
• W2022947570 hasVolume "35" @default.

• next