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- W2022956590 abstract "Determination of left ventricular myocardial (LV) mass may aid evaluation of hypertrophic cardiomyopathies and may provide a means for future determination of the percent viable myocardium with prognostic application in ischemic heart disease. The validity of cardiac MRI for determination of LV mass was experimentally evaluated in 5 dogs that were studied using a Diasonics superconducting magnet operating at 0.35 Tesla. Gated sign echo pulsing sequences were used obtaining 0.7 cm thick slices of the heart, spaced by 1 cm, in three orthogonal planes (transaxial, sagittal and coronal). The dogs were then sacrificed and the nonbeating hearts were imaged in-situ without gating. Subsequently the excised LV weight was measured. On each short-axis (coronal) MR slice, the LV surface area was planimetered and multiplied by slice spacing to obtain slice volume. In order to avoid the partial volume effect, the MR volume of the apex was determined from the transaxial cuts. The MR LV volume thus obtained was multiplied by the specific gravity of the myocardium (1.05) to determine the MR LV mass. The intra- and inter-observer agreement for planimetry of the MR images was high (r=.99 and r=.97, respectively), reflecting the high resolution of MRI for endocardial and epicardial edges. Nonbeating heart MRI and measured LV mass correlated highly (r=.99). In two dogs preliminary analysis by MRI of the in-vivo beating heart also showed close correlation with measured LV weight. Thus, cardiac MRI is a reproducible and accurate method for noninvasive determination of LV myocardial mass in-situ and offers potential for accurate in-vivo assessment." @default.
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- W2022956590 date "1984-09-01" @default.
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- W2022956590 title "CARDIAC MAGNETIC RESONANCE IMAGING (MRI) FOR NONINVASIVE QUANTIFICATION OF LEFT VENTRICULAR MYOCARDIAL MASS" @default.
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