FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022963144> ?p ?o ?g. }

• W2022963144 endingPage "305" @default.
• W2022963144 startingPage "298" @default.
• W2022963144 abstract "Abstract Rheumatoid arthritis ( RA ) is one of the autoimmune diseases, where different polymorphisms in cytokine genes play a pathogenic role. Interleukin 27 ( IL ‐27) is a novel pro‐/anti‐inflammatory cytokine, an excellent candidate for chronic inflammatory disease studies. The aim of the study was to identify polymorphisms in the IL ‐27 gene and their possible association with susceptibility to and severity of RA . Two hundred and seventy‐four patients with RA and of 295 healthy individuals were examined for −924 A / G and 4730 T / C IL 27 gene polymorphisms using PCR ‐ RFLP method and T aq M an SNP genotyping assay, respectively. Haplotype frequencies of IL ‐27 polymorphisms were estimated using SHE sis platform. Frequencies of the −924 GG genotype and the −924 G allele were statistically higher in RA patients comparing with the healthy control group ( P = 0.008 and P = 0.004, respectively). Overall, strong LD was observed between the IL 27 gene −924 A / G and 4730 T / C polymorphisms (D′ = 0.613, r2 = 0.199). From four possible haplotypes, frequencies of two ( CA and CG ) showed significant differences between both examined groups (respectively: P < 0.001 and P = 0.001062). The genotype–phenotype analysis showed significant association between the IL ‐27 4730 T / C polymorphism and HAQ score and means value of the ESR , additionally they revealed that individuals with the polymorphic allele −924 G had more advanced disease than wild‐type allele carriers. Present findings indicated that IL 27 −924 A / G polymorphism may be involved in susceptibility to RA in the Polish population." @default.
• W2022963144 created "2016-06-24" @default.
• W2022963144 creator A5003538370 @default.
• W2022963144 creator A5039583864 @default.
• W2022963144 creator A5050514107 @default.
• W2022963144 creator A5060654505 @default.
• W2022963144 creator A5064601460 @default.
• W2022963144 creator A5078074425 @default.
• W2022963144 creator A5083149291 @default.
• W2022963144 date "2014-09-16" @default.
• W2022963144 modified "2023-10-18" @default.
• W2022963144 title "Association of Single Nucleotide Polymorphisms in the<i>IL27</i>Gene with Rheumatoid Arthritis" @default.
• W2022963144 cites W1514704168 @default.
• W2022963144 cites W1837092909 @default.
• W2022963144 cites W1854638296 @default.
• W2022963144 cites W1964470959 @default.
• W2022963144 cites W1967880985 @default.
• W2022963144 cites W1970142265 @default.
• W2022963144 cites W1981359098 @default.
• W2022963144 cites W1992163151 @default.
• W2022963144 cites W1992702174 @default.
• W2022963144 cites W2005697963 @default.
• W2022963144 cites W2016956768 @default.
• W2022963144 cites W2025642324 @default.
• W2022963144 cites W2031853418 @default.
• W2022963144 cites W2039596320 @default.
• W2022963144 cites W2049690086 @default.
• W2022963144 cites W2055309000 @default.
• W2022963144 cites W2103412051 @default.
• W2022963144 cites W2104300626 @default.
• W2022963144 cites W2117818892 @default.
• W2022963144 cites W2141511965 @default.
• W2022963144 cites W2149473602 @default.
• W2022963144 cites W2151566241 @default.
• W2022963144 cites W4294468239 @default.
• W2022963144 doi "https://doi.org/10.1111/sji.12209" @default.
• W2022963144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25041531" @default.
• W2022963144 hasPublicationYear "2014" @default.
• W2022963144 type Work @default.
• W2022963144 sameAs 2022963144 @default.
• W2022963144 citedByCount "28" @default.
• W2022963144 countsByYear W20229631442015 @default.
• W2022963144 countsByYear W20229631442016 @default.
• W2022963144 countsByYear W20229631442017 @default.
• W2022963144 countsByYear W20229631442018 @default.
• W2022963144 countsByYear W20229631442019 @default.
• W2022963144 countsByYear W20229631442020 @default.
• W2022963144 countsByYear W20229631442021 @default.
• W2022963144 countsByYear W20229631442022 @default.
• W2022963144 crossrefType "journal-article" @default.
• W2022963144 hasAuthorship W2022963144A5003538370 @default.
• W2022963144 hasAuthorship W2022963144A5039583864 @default.
• W2022963144 hasAuthorship W2022963144A5050514107 @default.
• W2022963144 hasAuthorship W2022963144A5060654505 @default.
• W2022963144 hasAuthorship W2022963144A5064601460 @default.
• W2022963144 hasAuthorship W2022963144A5078074425 @default.
• W2022963144 hasAuthorship W2022963144A5083149291 @default.
• W2022963144 hasConcept C104317684 @default.
• W2022963144 hasConcept C135763542 @default.
• W2022963144 hasConcept C139275648 @default.
• W2022963144 hasConcept C149737253 @default.
• W2022963144 hasConcept C153209595 @default.
• W2022963144 hasConcept C180754005 @default.
• W2022963144 hasConcept C197754878 @default.
• W2022963144 hasConcept C203014093 @default.
• W2022963144 hasConcept C2777575956 @default.
• W2022963144 hasConcept C31467283 @default.
• W2022963144 hasConcept C37463918 @default.
• W2022963144 hasConcept C54355233 @default.
• W2022963144 hasConcept C71924100 @default.
• W2022963144 hasConcept C86803240 @default.
• W2022963144 hasConceptScore W2022963144C104317684 @default.
• W2022963144 hasConceptScore W2022963144C135763542 @default.
• W2022963144 hasConceptScore W2022963144C139275648 @default.
• W2022963144 hasConceptScore W2022963144C149737253 @default.
• W2022963144 hasConceptScore W2022963144C153209595 @default.
• W2022963144 hasConceptScore W2022963144C180754005 @default.
• W2022963144 hasConceptScore W2022963144C197754878 @default.
• W2022963144 hasConceptScore W2022963144C203014093 @default.
• W2022963144 hasConceptScore W2022963144C2777575956 @default.
• W2022963144 hasConceptScore W2022963144C31467283 @default.
• W2022963144 hasConceptScore W2022963144C37463918 @default.
• W2022963144 hasConceptScore W2022963144C54355233 @default.
• W2022963144 hasConceptScore W2022963144C71924100 @default.
• W2022963144 hasConceptScore W2022963144C86803240 @default.
• W2022963144 hasIssue "4" @default.
• W2022963144 hasLocation W20229631441 @default.
• W2022963144 hasOpenAccess W2022963144 @default.
• W2022963144 hasPrimaryLocation W20229631441 @default.
• W2022963144 hasRelatedWork W1901150897 @default.
• W2022963144 hasRelatedWork W1966708416 @default.
• W2022963144 hasRelatedWork W2021538970 @default.
• W2022963144 hasRelatedWork W2164332050 @default.
• W2022963144 hasRelatedWork W2184363627 @default.
• W2022963144 hasRelatedWork W2283861756 @default.
• W2022963144 hasRelatedWork W2327017833 @default.
• W2022963144 hasRelatedWork W2348076134 @default.
• W2022963144 hasRelatedWork W2360977025 @default.

• next