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• W2022963520 abstract "In Brief BACKGROUND: We examined in this randomized, double-blind study whether a multilevel paravertebral block performed before general anesthesia with propofol and a laryngeal mask enhances postoperative analgesia after breast cancer surgery. METHODS: Eighty-eight patients were randomized to receive paravertebral injections with either ropivacaine 0.5% (30 mL) or an equivalent amount of isotonic saline. Nine patients were excluded after randomization, thus 79 patients remained for evaluation (ropivacaine, n = 38; placebo, n = 41). Variables of efficacy were the amount of fentanyl delivered by the patient-controlled analgesia device in the postanesthesia care unit (PACU), postoperative pain measured on a numeric rating scale at regular intervals from the day of surgery and until the second postoperative day. RESULTS: The median consumption of fentanyl in the PACU was less in the ropivacaine group compared with the placebo group (0 μg [range: 0–250 μg] versus 100 μg [range: 0–800 μg], P = 0.001). Also, fewer patients in the ropivacaine group reported pain ≥3 on the numbers rating scale in the PACU (13 vs 31, P < 0.0001). No statistical difference in pain scores or consumption of analgesics could be demonstrated after discharge from the PACU. CONCLUSIONS: A multilevel paravertebral block provides good analgesia for breast surgery, but the duration of analgesia is briefer than described in previous studies. IMPLICATIONS: A multilevel paravertebral block provides good analgesia for breast surgery, but the duration of analgesia is briefer than described in previous studies." @default.
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• W2022963520 date "2007-12-01" @default.
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• W2022963520 title "Thoracic Paravertebral Block for Breast Cancer Surgery: A Randomized Double-Blind Study" @default.
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• W2022963520 doi "https://doi.org/10.1213/01.ane.0000286135.21333.fd" @default.
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