FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022973850> ?p ?o ?g. }

• W2022973850 endingPage "164" @default.
• W2022973850 startingPage "161" @default.
• W2022973850 abstract "La fiebre chikungunya es una enfermedad producida por un alfavirus perteneciente a la familia Togaviridae, transmitida por miembros de diferentes especies del género Aedes: Aedes aegypti y Aedes albopictus (A. albopictus). Es endémica en África y Asia, ocasionando brotes epidémicos recurrentes. En 2007, surge de forma emergente en Europa transmitida por A. albopictus, asentado en el área mediterránea. Los primeros casos autóctonos detectados recientemente en las islas caribeñas suponen una seria amenaza de propagación al continente americano, libre hasta el momento de la enfermedad. Se manifiesta de forma aguda con fiebre, rash cutáneo y poliartritis. La mortalidad es baja, pero un porcentaje elevado de enfermos desarrollan una fase crónica definida por poliartritis persistente durante meses e incluso años. Una severa reacción inmunitaria de defensa con incremento de citocinas proinflamatorias es la responsable de la inflamación articular. El tratamiento es sintomático. No disponemos de terapia antiviral específica ni vacuna preventiva. Por ello, debemos profundizar en el estudio de la inmunopatogénesis, con el fin encontrar dianas terapéuticas más apropiadas. Chikungunya fever is a viral disease caused by an alphavirus belonging to the Togaviridae family, transmitted by several species of Aedes mosquitoes: Aedes aegypti and Aedes albopictus (A. albopictus). It is endemic in Africa and Asia with recurrent outbreaks. It is an emerging disease and cases in Europe transmitted by A. albopictus have been established in Mediterranean areas. The first autochthonous cases detected on the Caribbean islands suppose a serious threat of spreading disease to America, which so far has been disease free. Clinical symptoms begin abruptly with fever, skin rash and polyarthritis. Although mortality is low, a high percentage of patients develop a chronic phase defined by persistent arthritis for months or even years. A severe immune response is responsible for joint inflammation. The absence of specific treatment and lack of vaccine requires detailed studies about its immunopathogenesis in order to determine the most appropriate target." @default.
• W2022973850 created "2016-06-24" @default.
• W2022973850 creator A5005773339 @default.
• W2022973850 creator A5006222572 @default.
• W2022973850 creator A5012544467 @default.
• W2022973850 date "2015-05-01" @default.
• W2022973850 modified "2023-09-27" @default.
• W2022973850 title "Fiebre chikungunya. Manifestaciones reumáticas de una infección emergente en Europa" @default.
• W2022973850 cites W1912423637 @default.
• W2022973850 cites W1970548365 @default.
• W2022973850 cites W1975959045 @default.
• W2022973850 cites W1991213950 @default.
• W2022973850 cites W2022342738 @default.
• W2022973850 cites W202547093 @default.
• W2022973850 cites W2039313694 @default.
• W2022973850 cites W2068012691 @default.
• W2022973850 cites W2076193648 @default.
• W2022973850 cites W2084699759 @default.
• W2022973850 cites W2097446992 @default.
• W2022973850 cites W2104987209 @default.
• W2022973850 cites W2112497696 @default.
• W2022973850 cites W2120801593 @default.
• W2022973850 cites W2127427126 @default.
• W2022973850 cites W2130559172 @default.
• W2022973850 cites W2136176601 @default.
• W2022973850 cites W2141987735 @default.
• W2022973850 cites W2148371183 @default.
• W2022973850 cites W2155223233 @default.
• W2022973850 cites W2321775884 @default.
• W2022973850 doi "https://doi.org/10.1016/j.reuma.2014.07.005" @default.
• W2022973850 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25192946" @default.
• W2022973850 hasPublicationYear "2015" @default.
• W2022973850 type Work @default.
• W2022973850 sameAs 2022973850 @default.
• W2022973850 citedByCount "30" @default.
• W2022973850 countsByYear W20229738502015 @default.
• W2022973850 countsByYear W20229738502016 @default.
• W2022973850 countsByYear W20229738502017 @default.
• W2022973850 countsByYear W20229738502018 @default.
• W2022973850 countsByYear W20229738502019 @default.
• W2022973850 countsByYear W20229738502020 @default.
• W2022973850 countsByYear W20229738502021 @default.
• W2022973850 crossrefType "journal-article" @default.
• W2022973850 hasAuthorship W2022973850A5005773339 @default.
• W2022973850 hasAuthorship W2022973850A5006222572 @default.
• W2022973850 hasAuthorship W2022973850A5012544467 @default.
• W2022973850 hasConcept C142362112 @default.
• W2022973850 hasConcept C15708023 @default.
• W2022973850 hasConcept C159047783 @default.
• W2022973850 hasConcept C173758957 @default.
• W2022973850 hasConcept C2776853612 @default.
• W2022973850 hasConcept C2777775583 @default.
• W2022973850 hasConcept C2781273456 @default.
• W2022973850 hasConcept C533803919 @default.
• W2022973850 hasConcept C59822182 @default.
• W2022973850 hasConcept C71924100 @default.
• W2022973850 hasConcept C86803240 @default.
• W2022973850 hasConceptScore W2022973850C142362112 @default.
• W2022973850 hasConceptScore W2022973850C15708023 @default.
• W2022973850 hasConceptScore W2022973850C159047783 @default.
• W2022973850 hasConceptScore W2022973850C173758957 @default.
• W2022973850 hasConceptScore W2022973850C2776853612 @default.
• W2022973850 hasConceptScore W2022973850C2777775583 @default.
• W2022973850 hasConceptScore W2022973850C2781273456 @default.
• W2022973850 hasConceptScore W2022973850C533803919 @default.
• W2022973850 hasConceptScore W2022973850C59822182 @default.
• W2022973850 hasConceptScore W2022973850C71924100 @default.
• W2022973850 hasConceptScore W2022973850C86803240 @default.
• W2022973850 hasIssue "3" @default.
• W2022973850 hasLocation W20229738501 @default.
• W2022973850 hasLocation W20229738502 @default.
• W2022973850 hasOpenAccess W2022973850 @default.
• W2022973850 hasPrimaryLocation W20229738501 @default.
• W2022973850 hasRelatedWork W1510648115 @default.
• W2022973850 hasRelatedWork W2087651807 @default.
• W2022973850 hasRelatedWork W2342341740 @default.
• W2022973850 hasRelatedWork W2620876971 @default.
• W2022973850 hasRelatedWork W2884836828 @default.
• W2022973850 hasRelatedWork W2992862443 @default.
• W2022973850 hasRelatedWork W3024958360 @default.
• W2022973850 hasRelatedWork W3102318761 @default.
• W2022973850 hasRelatedWork W3215161474 @default.
• W2022973850 hasRelatedWork W4386142822 @default.
• W2022973850 hasVolume "11" @default.
• W2022973850 isParatext "false" @default.
• W2022973850 isRetracted "false" @default.
• W2022973850 magId "2022973850" @default.
• W2022973850 workType "article" @default.