FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022976083> ?p ?o ?g. }

• W2022976083 endingPage "e41143" @default.
• W2022976083 startingPage "e41143" @default.
• W2022976083 abstract "DNA methylation is sensitive and responsive to stressful environmental conditions. Nonetheless, the extent to which condition-induced somatic methylation modifications can impose transgenerational effects remains to be fully understood. Even less is known about the biological relevance of the induced epigenetic changes for potentially altered well-being of the organismal progenies regarding adaptation to the specific condition their progenitors experienced.We analyzed DNA methylation pattern by gel-blotting at genomic loci representing transposable elements and protein-coding genes in leaf-tissue of heavy metal-treated rice (Oryza sativa) plants (S0), and its three successive organismal generations. We assessed expression of putative genes involved in establishing and/or maintaining DNA methylation patterns by reverse transcription (RT)-PCR. We measured growth of the stressed plants and their unstressed progenies vs. the control plants. We found (1) relative to control, DNA methylation patterns were modified in leaf-tissue of the immediately treated plants, and the modifications were exclusively confined to CHG hypomethylation; (2) the CHG-demethylated states were heritable via both maternal and paternal germline, albeit often accompanying further hypomethylation; (3) altered expression of genes encoding for DNA methyltransferases, DNA glycosylase and SWI/SNF chromatin remodeling factor (DDM1) were induced by the stress; (4) progenies of the stressed plants exhibited enhanced tolerance to the same stress their progenitor experienced, and this transgenerational inheritance of the effect of condition accompanying heritability of modified methylation patterns.Our findings suggest that stressful environmental condition can produce transgenerational epigenetic modifications. Progenies of stressed plants may develop enhanced adaptability to the condition, and this acquired trait is inheritable and accord with transmission of the epigenetic modifications. We suggest that environmental induction of heritable modifications in DNA methylation provides a plausible molecular underpinning for the still contentious paradigm of inheritance of acquired traits originally put forward by Jean-Baptiste Lamarck more than 200 years ago." @default.
• W2022976083 created "2016-06-24" @default.
• W2022976083 creator A5008951787 @default.
• W2022976083 creator A5015862863 @default.
• W2022976083 creator A5017590194 @default.
• W2022976083 creator A5023119724 @default.
• W2022976083 creator A5042099328 @default.
• W2022976083 creator A5042442643 @default.
• W2022976083 creator A5049654863 @default.
• W2022976083 creator A5056372539 @default.
• W2022976083 creator A5065933713 @default.
• W2022976083 date "2012-09-11" @default.
• W2022976083 modified "2023-10-11" @default.
• W2022976083 title "Transgenerational Inheritance of Modified DNA Methylation Patterns and Enhanced Tolerance Induced by Heavy Metal Stress in Rice (Oryza sativa L.)" @default.
• W2022976083 cites W1500702901 @default.
• W2022976083 cites W1530778430 @default.
• W2022976083 cites W1604521274 @default.
• W2022976083 cites W1653671659 @default.
• W2022976083 cites W1889938952 @default.
• W2022976083 cites W1964271596 @default.
• W2022976083 cites W1965428844 @default.
• W2022976083 cites W1967609877 @default.
• W2022976083 cites W1967718380 @default.
• W2022976083 cites W1973960846 @default.
• W2022976083 cites W1974907033 @default.
• W2022976083 cites W1977171359 @default.
• W2022976083 cites W1979733539 @default.
• W2022976083 cites W1987104387 @default.
• W2022976083 cites W1994545768 @default.
• W2022976083 cites W2005937797 @default.
• W2022976083 cites W2012302404 @default.
• W2022976083 cites W2015305713 @default.
• W2022976083 cites W2019896138 @default.
• W2022976083 cites W2026343134 @default.
• W2022976083 cites W2030819518 @default.
• W2022976083 cites W2032506756 @default.
• W2022976083 cites W2032879466 @default.
• W2022976083 cites W2037797217 @default.
• W2022976083 cites W2042948064 @default.
• W2022976083 cites W2050507681 @default.
• W2022976083 cites W2052041575 @default.
• W2022976083 cites W2052439644 @default.
• W2022976083 cites W2056558781 @default.
• W2022976083 cites W2070366764 @default.
• W2022976083 cites W2071806650 @default.
• W2022976083 cites W2083796290 @default.
• W2022976083 cites W2085338556 @default.
• W2022976083 cites W2090912314 @default.
• W2022976083 cites W2097390770 @default.
• W2022976083 cites W2101814858 @default.
• W2022976083 cites W2111659126 @default.
• W2022976083 cites W2121304801 @default.
• W2022976083 cites W2127460368 @default.
• W2022976083 cites W2128450665 @default.
• W2022976083 cites W2129300527 @default.
• W2022976083 cites W2134646410 @default.
• W2022976083 cites W2138766691 @default.
• W2022976083 cites W2141887265 @default.
• W2022976083 cites W2142979837 @default.
• W2022976083 cites W2147325012 @default.
• W2022976083 cites W2156775422 @default.
• W2022976083 cites W2157507378 @default.
• W2022976083 cites W2163250539 @default.
• W2022976083 cites W2410345316 @default.
• W2022976083 doi "https://doi.org/10.1371/journal.pone.0041143" @default.
• W2022976083 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3439459" @default.
• W2022976083 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22984395" @default.
• W2022976083 hasPublicationYear "2012" @default.
• W2022976083 type Work @default.
• W2022976083 sameAs 2022976083 @default.
• W2022976083 citedByCount "153" @default.
• W2022976083 countsByYear W20229760832013 @default.
• W2022976083 countsByYear W20229760832014 @default.
• W2022976083 countsByYear W20229760832015 @default.
• W2022976083 countsByYear W20229760832016 @default.
• W2022976083 countsByYear W20229760832017 @default.
• W2022976083 countsByYear W20229760832018 @default.
• W2022976083 countsByYear W20229760832019 @default.
• W2022976083 countsByYear W20229760832020 @default.
• W2022976083 countsByYear W20229760832021 @default.
• W2022976083 countsByYear W20229760832022 @default.
• W2022976083 countsByYear W20229760832023 @default.
• W2022976083 crossrefType "journal-article" @default.
• W2022976083 hasAuthorship W2022976083A5008951787 @default.
• W2022976083 hasAuthorship W2022976083A5015862863 @default.
• W2022976083 hasAuthorship W2022976083A5017590194 @default.
• W2022976083 hasAuthorship W2022976083A5023119724 @default.
• W2022976083 hasAuthorship W2022976083A5042099328 @default.
• W2022976083 hasAuthorship W2022976083A5042442643 @default.
• W2022976083 hasAuthorship W2022976083A5049654863 @default.
• W2022976083 hasAuthorship W2022976083A5056372539 @default.
• W2022976083 hasAuthorship W2022976083A5065933713 @default.
• W2022976083 hasBestOaLocation W20229760831 @default.
• W2022976083 hasConcept C104317684 @default.
• W2022976083 hasConcept C141231307 @default.
• W2022976083 hasConcept C150194340 @default.
• W2022976083 hasConcept C190727270 @default.
• W2022976083 hasConcept C2778543611 @default.

• next