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- W2022982606 abstract "Abstract Purpose: Hodgkin lymphoma (HL) survivors are susceptible to long-term side effects from definitive treatment with combination chemotherapy and radiation therapy (RT). Because late effects from RT correlate to radiation treatment volume, stage III/IV pediatric HL requiring large radiation fields are at greater risk for late complications. This study investigates the dosimetric impact of proton therapy (PT) to spare the organs at risk (OARs) in stage III and IV HL. Patients and Methods: From October 2011 through January 2014, 7 pediatric patients with stage III or IV HL involving both supradiaphragmatic and infradiaphragmatic underwent treatment planning with 3-dimensional conformal radiation therapy (3DCRT), intensity-modulated radiation therapy (IMRT), and PT to a dose of 21 Gy after ABVE-PC chemotherapy. Plans were normalized to meet treatment parameters including target coverage and dose to OARs. Results: All 7 patients were treated with PT. PT had the lowest integral body dose (101 J; range, 5..." @default.
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- W2022982606 date "2014-09-01" @default.
- W2022982606 modified "2023-09-23" @default.
- W2022982606 title "Advancing the Therapeutic Index in Stage III/IV Pediatric Hodgkin Lymphoma with Proton Therapy" @default.
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- W2022982606 doi "https://doi.org/10.14338/ijpt.14.00001.1" @default.
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