Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022984044> ?p ?o ?g. }
- W2022984044 endingPage "1653" @default.
- W2022984044 startingPage "1646" @default.
- W2022984044 abstract "The NOTCH signaling pathway performs a wide range of critical functions in a number of different cell types during development and differentiation. The role of NOTCH signals in human embryonic stem cells (hESCs) has not been tested. We measured the activity of canonical NOTCH signaling in undifferentiated embryonic stem (ES) cells and tested the requirement for NOTCH activity in hESC self-renewal or differentiation by growing hESCs in the presence of gamma-secretase inhibitors. Our results suggest that NOTCH signaling is not required for the propagation of undifferentiated human ES cells but instead is required for the maintenance of the differentiating cell types that accumulate in human ES cell cultures. Our studies suggest that NOTCH signaling is not required in human embryonic differentiation until the formation of extraembryonic, germ layer, or tissue-specific stem cells and progenitors." @default.
- W2022984044 created "2016-06-24" @default.
- W2022984044 creator A5046445522 @default.
- W2022984044 creator A5067007394 @default.
- W2022984044 creator A5085004189 @default.
- W2022984044 date "2006-07-01" @default.
- W2022984044 modified "2023-10-16" @default.
- W2022984044 title "Notch Signaling Is Inactive but Inducible in Human Embryonic Stem Cells" @default.
- W2022984044 cites W1532405552 @default.
- W2022984044 cites W1567624342 @default.
- W2022984044 cites W1599568627 @default.
- W2022984044 cites W1911156364 @default.
- W2022984044 cites W1966828612 @default.
- W2022984044 cites W1975141582 @default.
- W2022984044 cites W1991148912 @default.
- W2022984044 cites W1999504956 @default.
- W2022984044 cites W2002093986 @default.
- W2022984044 cites W2005296007 @default.
- W2022984044 cites W2012660316 @default.
- W2022984044 cites W2016460139 @default.
- W2022984044 cites W2016668224 @default.
- W2022984044 cites W2026596383 @default.
- W2022984044 cites W2028312858 @default.
- W2022984044 cites W2055335794 @default.
- W2022984044 cites W2066413879 @default.
- W2022984044 cites W2067062988 @default.
- W2022984044 cites W2067809243 @default.
- W2022984044 cites W2074683943 @default.
- W2022984044 cites W2077040170 @default.
- W2022984044 cites W2080811177 @default.
- W2022984044 cites W2082694975 @default.
- W2022984044 cites W2083763893 @default.
- W2022984044 cites W2083904945 @default.
- W2022984044 cites W2084421599 @default.
- W2022984044 cites W2089426706 @default.
- W2022984044 cites W2091475538 @default.
- W2022984044 cites W2103118693 @default.
- W2022984044 cites W2106963389 @default.
- W2022984044 cites W2110301828 @default.
- W2022984044 cites W2138088258 @default.
- W2022984044 cites W2140909735 @default.
- W2022984044 cites W2147507075 @default.
- W2022984044 cites W2154861644 @default.
- W2022984044 cites W2160266371 @default.
- W2022984044 cites W2161949020 @default.
- W2022984044 cites W2163102268 @default.
- W2022984044 cites W2167808312 @default.
- W2022984044 cites W2833026885 @default.
- W2022984044 doi "https://doi.org/10.1634/stemcells.2005-0314" @default.
- W2022984044 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16614005" @default.
- W2022984044 hasPublicationYear "2006" @default.
- W2022984044 type Work @default.
- W2022984044 sameAs 2022984044 @default.
- W2022984044 citedByCount "39" @default.
- W2022984044 countsByYear W20229840442012 @default.
- W2022984044 countsByYear W20229840442013 @default.
- W2022984044 countsByYear W20229840442014 @default.
- W2022984044 countsByYear W20229840442015 @default.
- W2022984044 countsByYear W20229840442016 @default.
- W2022984044 countsByYear W20229840442018 @default.
- W2022984044 countsByYear W20229840442019 @default.
- W2022984044 countsByYear W20229840442021 @default.
- W2022984044 crossrefType "journal-article" @default.
- W2022984044 hasAuthorship W2022984044A5046445522 @default.
- W2022984044 hasAuthorship W2022984044A5067007394 @default.
- W2022984044 hasAuthorship W2022984044A5085004189 @default.
- W2022984044 hasBestOaLocation W20229840441 @default.
- W2022984044 hasConcept C104317684 @default.
- W2022984044 hasConcept C107459253 @default.
- W2022984044 hasConcept C143948831 @default.
- W2022984044 hasConcept C145103041 @default.
- W2022984044 hasConcept C148738053 @default.
- W2022984044 hasConcept C161879069 @default.
- W2022984044 hasConcept C18155467 @default.
- W2022984044 hasConcept C201750760 @default.
- W2022984044 hasConcept C202769670 @default.
- W2022984044 hasConcept C20875687 @default.
- W2022984044 hasConcept C28328180 @default.
- W2022984044 hasConcept C54355233 @default.
- W2022984044 hasConcept C62478195 @default.
- W2022984044 hasConcept C65114990 @default.
- W2022984044 hasConcept C86803240 @default.
- W2022984044 hasConcept C95444343 @default.
- W2022984044 hasConceptScore W2022984044C104317684 @default.
- W2022984044 hasConceptScore W2022984044C107459253 @default.
- W2022984044 hasConceptScore W2022984044C143948831 @default.
- W2022984044 hasConceptScore W2022984044C145103041 @default.
- W2022984044 hasConceptScore W2022984044C148738053 @default.
- W2022984044 hasConceptScore W2022984044C161879069 @default.
- W2022984044 hasConceptScore W2022984044C18155467 @default.
- W2022984044 hasConceptScore W2022984044C201750760 @default.
- W2022984044 hasConceptScore W2022984044C202769670 @default.
- W2022984044 hasConceptScore W2022984044C20875687 @default.
- W2022984044 hasConceptScore W2022984044C28328180 @default.
- W2022984044 hasConceptScore W2022984044C54355233 @default.
- W2022984044 hasConceptScore W2022984044C62478195 @default.
- W2022984044 hasConceptScore W2022984044C65114990 @default.
- W2022984044 hasConceptScore W2022984044C86803240 @default.