FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022989929> ?p ?o ?g. }

• W2022989929 endingPage "187" @default.
• W2022989929 startingPage "181" @default.
• W2022989929 abstract "In several animal studies, prolactin has been found to be essential for mammary epithelial development, and its administration has been consistently shown to increase the rate of mammary tumours. High levels of steroid hormones have also been suggested to enhance mammary cancer development. The present study investigates the levels of the following hormones in serum and in tissue homogenates in dogs bearing canine mammary tumours: prolactin (PRL), progesterone (P4), dehydroepiandrosterone (DHEA), androstenedione (A4), testosterone (T), 17beta-estradiol (17beta-E2) and estrone sulfate (S04E1). Eighty mammary tumours (40 dysplasias and benign and 40 malignant tumours) from 32 female dogs, and 10 normal mammary glands from eight female dogs without history of mammary tumours, were analysed. Prolactin and steroid hormones in serum and tissue homogenates, were analysed by enzyme immunoassays (EIA) techniques, previously validated for this animal species. Levels of prolactin in tissue homogenates were significantly different between malignant and benign mammary tumours (p<0.01). Serum prolactin concentrations were lower in the control group as compared with the group of dogs with benign tumours and in dogs with malignant tumours (p=0.01). Serum prolactin levels in dogs with benign lesions were not significantly different than those obtained from dogs with malignant tumours. Levels of steroid hormones were significantly higher in malignant tumours compared with the benign tumours and normal mammary glands (p<0.01) both in serum and homogenate determinations. Our results suggest that the canine neoplastic mammary gland could be a source of prolactin. Our hypothesis is that both prolactin and steroid hormones are involved in the growth of canine mammary cancer, and that they might have an autocrine/paracrine role in the maintenance of this disease." @default.
• W2022989929 created "2016-06-24" @default.
• W2022989929 creator A5023101147 @default.
• W2022989929 creator A5025795157 @default.
• W2022989929 creator A5035806644 @default.
• W2022989929 creator A5059822479 @default.
• W2022989929 creator A5070361730 @default.
• W2022989929 creator A5082370143 @default.
• W2022989929 date "2005-02-01" @default.
• W2022989929 modified "2023-10-17" @default.
• W2022989929 title "Role of steroid hormones and prolactin in canine mammary cancer" @default.
• W2022989929 cites W124018961 @default.
• W2022989929 cites W1268960040 @default.
• W2022989929 cites W1512196280 @default.
• W2022989929 cites W1883434296 @default.
• W2022989929 cites W1964033127 @default.
• W2022989929 cites W1969890794 @default.
• W2022989929 cites W1970085289 @default.
• W2022989929 cites W1992367546 @default.
• W2022989929 cites W1994896959 @default.
• W2022989929 cites W1998002970 @default.
• W2022989929 cites W2001431697 @default.
• W2022989929 cites W2003463981 @default.
• W2022989929 cites W2011501880 @default.
• W2022989929 cites W2013519213 @default.
• W2022989929 cites W2013733324 @default.
• W2022989929 cites W2023523424 @default.
• W2022989929 cites W2026264021 @default.
• W2022989929 cites W2026297700 @default.
• W2022989929 cites W2038974551 @default.
• W2022989929 cites W2042464257 @default.
• W2022989929 cites W2051360627 @default.
• W2022989929 cites W2054286532 @default.
• W2022989929 cites W2074625888 @default.
• W2022989929 cites W2099328865 @default.
• W2022989929 cites W2105028526 @default.
• W2022989929 cites W2113103296 @default.
• W2022989929 cites W2114438201 @default.
• W2022989929 cites W2129226890 @default.
• W2022989929 cites W2138453236 @default.
• W2022989929 cites W2142858455 @default.
• W2022989929 cites W2144104692 @default.
• W2022989929 cites W2172227230 @default.
• W2022989929 cites W2282688871 @default.
• W2022989929 cites W2315818624 @default.
• W2022989929 cites W4234123851 @default.
• W2022989929 doi "https://doi.org/10.1016/j.jsbmb.2004.12.014" @default.
• W2022989929 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15862964" @default.
• W2022989929 hasPublicationYear "2005" @default.
• W2022989929 type Work @default.
• W2022989929 sameAs 2022989929 @default.
• W2022989929 citedByCount "65" @default.
• W2022989929 countsByYear W20229899292012 @default.
• W2022989929 countsByYear W20229899292013 @default.
• W2022989929 countsByYear W20229899292014 @default.
• W2022989929 countsByYear W20229899292015 @default.
• W2022989929 countsByYear W20229899292016 @default.
• W2022989929 countsByYear W20229899292017 @default.
• W2022989929 countsByYear W20229899292018 @default.
• W2022989929 countsByYear W20229899292019 @default.
• W2022989929 countsByYear W20229899292020 @default.
• W2022989929 countsByYear W20229899292021 @default.
• W2022989929 countsByYear W20229899292022 @default.
• W2022989929 countsByYear W20229899292023 @default.
• W2022989929 crossrefType "journal-article" @default.
• W2022989929 hasAuthorship W2022989929A5023101147 @default.
• W2022989929 hasAuthorship W2022989929A5025795157 @default.
• W2022989929 hasAuthorship W2022989929A5035806644 @default.
• W2022989929 hasAuthorship W2022989929A5059822479 @default.
• W2022989929 hasAuthorship W2022989929A5070361730 @default.
• W2022989929 hasAuthorship W2022989929A5082370143 @default.
• W2022989929 hasConcept C121608353 @default.
• W2022989929 hasConcept C126322002 @default.
• W2022989929 hasConcept C134018914 @default.
• W2022989929 hasConcept C2776187077 @default.
• W2022989929 hasConcept C2776683971 @default.
• W2022989929 hasConcept C2776992908 @default.
• W2022989929 hasConcept C2777911890 @default.
• W2022989929 hasConcept C2778001805 @default.
• W2022989929 hasConcept C2778656385 @default.
• W2022989929 hasConcept C2779064019 @default.
• W2022989929 hasConcept C2779279991 @default.
• W2022989929 hasConcept C2780902042 @default.
• W2022989929 hasConcept C530470458 @default.
• W2022989929 hasConcept C71315377 @default.
• W2022989929 hasConcept C71924100 @default.
• W2022989929 hasConcept C86803240 @default.
• W2022989929 hasConceptScore W2022989929C121608353 @default.
• W2022989929 hasConceptScore W2022989929C126322002 @default.
• W2022989929 hasConceptScore W2022989929C134018914 @default.
• W2022989929 hasConceptScore W2022989929C2776187077 @default.
• W2022989929 hasConceptScore W2022989929C2776683971 @default.
• W2022989929 hasConceptScore W2022989929C2776992908 @default.
• W2022989929 hasConceptScore W2022989929C2777911890 @default.
• W2022989929 hasConceptScore W2022989929C2778001805 @default.
• W2022989929 hasConceptScore W2022989929C2778656385 @default.
• W2022989929 hasConceptScore W2022989929C2779064019 @default.
• W2022989929 hasConceptScore W2022989929C2779279991 @default.

• next