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- W2022993908 abstract "Cells of a methylcholanthrene-induced fibrosarcoma, injected intravenously into syngeneic C57Bl mice, generated tumour nodules (“metastases”) in the lungs. The number of tumour nodules was reduced in recipients whose spleens had been previously removed. This effect of splenectomy was specific (thymectomy did not affect the number of pulmonary metastases), and was greater if fewer tumour cells were injected. It was also observed that active immunization against the fibrosarcoma caused stronger inhibition of pulmonary metastases in splenectomized than in sham-operated mice." @default.
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- W2022993908 date "1973-01-15" @default.
- W2022993908 modified "2023-09-25" @default.
- W2022993908 title "The effect of splenectomy on fibrosarcoma “metastases” in lungs of mice" @default.
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- W2022993908 doi "https://doi.org/10.1002/ijc.2910110122" @default.
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