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- W2022993968 abstract "Respiratory syncytial virus (RSV), a member of the Paramyxoviridae family, encodes a small hydrophobic (SH) protein of unknown function. Parainfluenza virus 5 (PIV5), a prototypical paramyxovirus, also encodes an SH protein, which inhibits tumor necrosis factor alpha (TNF-alpha) signaling. In this study, recombinant PIV5 viruses without their own SH but containing RSV SH (from RSV strain A2 or B1) in its place (PIV5DeltaSH-RSV SH) and RSV lacking its own SH (RSVDeltaSH) were generated and analyzed. The results indicate that the SH protein of RSV has a function similar to that of PIV5 SH and that it can inhibit TNF-alpha signaling." @default.
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- W2022993968 date "2007-08-01" @default.
- W2022993968 modified "2023-10-01" @default.
- W2022993968 title "Function of the Respiratory Syncytial Virus Small Hydrophobic Protein" @default.
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- W2022993968 doi "https://doi.org/10.1128/jvi.02717-06" @default.
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