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- W2022996299 abstract "Molecular mechanisms generating the topographic organization of corticothalamic (CT) circuits, which comprise more than three-quarters of the synaptic inputs onto sensory relay neurons, and their interdependence with thalamocortical (TC) axon development are unknown. Using in utero electroporation-mediated gene transfer, we show that EphA7-mediated signaling on neocortical axons controls the within-nucleus topography of CT projections in the thalamus. Notably, CT axons that mis-express EphA7 do not shift the relative positioning of their pathway within the subcortical telencephalon (ST), indicating that they do not depend upon EphA7/ephrin-A signaling in the ST for establishing this topography. Moreover, mis-expression of cortical EphA7 results in disrupted topography of CT projections, but unchanged inter- and intra-areal topography of TC projections. Our results support a model in which EphA/ephrin-A signaling controls independently the precision with which CT and TC projections develop, yet is essential for establishing their topographic reciprocity." @default.
- W2022996299 created "2016-06-24" @default.
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- W2022996299 date "2005-11-01" @default.
- W2022996299 modified "2023-09-27" @default.
- W2022996299 title "Dissociation of Corticothalamic and Thalamocortical Axon Targeting by an EphA7-Mediated Mechanism" @default.
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- W2022996299 cites W1576952949 @default.
- W2022996299 cites W1932979133 @default.
- W2022996299 cites W1948718975 @default.
- W2022996299 cites W1966610514 @default.
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- W2022996299 cites W2037344427 @default.
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- W2022996299 doi "https://doi.org/10.1016/j.neuron.2005.09.021" @default.
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