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• W2023001077 abstract "The action of the coumarin-type drugs and related compounds is reviewed to their VKOR antagonistic effects. In our study, twenty 3-pyridinyl, pyrimidinyl and pyrazolyl-4-hydroxycoumarin derivatives were synthesized. A comparative in vivo (CT, PT determination) and in vitro (measurement of PIVKA-II levels) anticoagulant study with respect to warfarin showed that the synthesized compounds have different anticoagulant activities, the most prospective compounds were the 3-pyrazolyl-4-hydroxycoumarin derivatives." @default.
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• W2023001077 date "2010-05-01" @default.
• W2023001077 modified "2023-10-14" @default.
• W2023001077 title "Synthesis, anticoagulant and PIVKA-II induced by new 4-hydroxycoumarin derivatives" @default.
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• W2023001077 doi "https://doi.org/10.1016/j.bmc.2010.04.009" @default.
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