Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023001218> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2023001218 endingPage "394" @default.
- W2023001218 startingPage "387" @default.
- W2023001218 abstract "The aim of this study was to investigate circadian variation in concentrations of arachidonic acid (AA) metabolites in relation to the circadian pattern in bronchial patency. Blood samples were obtained at 4-hr intervals from 2000 of 1 day until 1400 of the next from 12 diurnally active asthmatic and six diurnally active non-asthmatic patients. Bloods were analyzed for the prostanoids thromboxane A2 (measured as stable metabolite 6-keto-PGF1a), PGE2 and PGF2a. Airways patency was assessed by self-measurement of peak expiratory flow (PEF). In asthmatics, circadian variation was detected in PEF as well as PGE2 and TXB2. The circadian trough of the PEF rhythm closely coincided with the circadian peak of the PGE2 and TXB2 rhythms. In the controls, the PEF was not circadian rhythmic. Of the AA metabolites only 6-keto-PGF1a exhibited 24-hr bioperiodicity in the controls. The controls exhibited a significantly higher circadian mean of PEF (P less than 0.001), while the asthmatics had a lower 24-hr average PGE2 but greater mean TXB2/PGE2 ratio. The obstructive effect caused by the overall 24-hr deficiency of PGE2 in asthmatics is possibly amplified by the increased of TXB2 during the early morning hours. This dissociation of the temporal patterns in TXB2 and PGE2 levels over the 24 hr is discussed as a characteristic finding for asthmatics." @default.
- W2023001218 created "2016-06-24" @default.
- W2023001218 creator A5007029174 @default.
- W2023001218 creator A5017933831 @default.
- W2023001218 creator A5039448667 @default.
- W2023001218 creator A5040140560 @default.
- W2023001218 creator A5061322979 @default.
- W2023001218 date "1988-01-01" @default.
- W2023001218 modified "2023-09-26" @default.
- W2023001218 title "Arachidonic Acid Metabolites and Their Orcadian Rhythm in Patients with Allergic Bronchial Asthma" @default.
- W2023001218 cites W1971133657 @default.
- W2023001218 cites W1984055557 @default.
- W2023001218 cites W2032992259 @default.
- W2023001218 cites W2040901635 @default.
- W2023001218 cites W2058994566 @default.
- W2023001218 cites W2081299047 @default.
- W2023001218 cites W2091017944 @default.
- W2023001218 doi "https://doi.org/10.3109/07420528809067783" @default.
- W2023001218 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3233695" @default.
- W2023001218 hasPublicationYear "1988" @default.
- W2023001218 type Work @default.
- W2023001218 sameAs 2023001218 @default.
- W2023001218 citedByCount "4" @default.
- W2023001218 countsByYear W20230012182019 @default.
- W2023001218 crossrefType "journal-article" @default.
- W2023001218 hasAuthorship W2023001218A5007029174 @default.
- W2023001218 hasAuthorship W2023001218A5017933831 @default.
- W2023001218 hasAuthorship W2023001218A5039448667 @default.
- W2023001218 hasAuthorship W2023001218A5040140560 @default.
- W2023001218 hasAuthorship W2023001218A5061322979 @default.
- W2023001218 hasConcept C121446783 @default.
- W2023001218 hasConcept C126322002 @default.
- W2023001218 hasConcept C134018914 @default.
- W2023001218 hasConcept C181199279 @default.
- W2023001218 hasConcept C185592680 @default.
- W2023001218 hasConcept C19720800 @default.
- W2023001218 hasConcept C2776042228 @default.
- W2023001218 hasConcept C2777477808 @default.
- W2023001218 hasConcept C2777956040 @default.
- W2023001218 hasConcept C2778078955 @default.
- W2023001218 hasConcept C2781080829 @default.
- W2023001218 hasConcept C55493867 @default.
- W2023001218 hasConcept C71924100 @default.
- W2023001218 hasConcept C89560881 @default.
- W2023001218 hasConceptScore W2023001218C121446783 @default.
- W2023001218 hasConceptScore W2023001218C126322002 @default.
- W2023001218 hasConceptScore W2023001218C134018914 @default.
- W2023001218 hasConceptScore W2023001218C181199279 @default.
- W2023001218 hasConceptScore W2023001218C185592680 @default.
- W2023001218 hasConceptScore W2023001218C19720800 @default.
- W2023001218 hasConceptScore W2023001218C2776042228 @default.
- W2023001218 hasConceptScore W2023001218C2777477808 @default.
- W2023001218 hasConceptScore W2023001218C2777956040 @default.
- W2023001218 hasConceptScore W2023001218C2778078955 @default.
- W2023001218 hasConceptScore W2023001218C2781080829 @default.
- W2023001218 hasConceptScore W2023001218C55493867 @default.
- W2023001218 hasConceptScore W2023001218C71924100 @default.
- W2023001218 hasConceptScore W2023001218C89560881 @default.
- W2023001218 hasIssue "4" @default.
- W2023001218 hasLocation W20230012181 @default.
- W2023001218 hasLocation W20230012182 @default.
- W2023001218 hasOpenAccess W2023001218 @default.
- W2023001218 hasPrimaryLocation W20230012181 @default.
- W2023001218 hasRelatedWork W1983217032 @default.
- W2023001218 hasRelatedWork W1986673839 @default.
- W2023001218 hasRelatedWork W1997915932 @default.
- W2023001218 hasRelatedWork W2059593117 @default.
- W2023001218 hasRelatedWork W2092341993 @default.
- W2023001218 hasRelatedWork W2101550646 @default.
- W2023001218 hasRelatedWork W2418909174 @default.
- W2023001218 hasRelatedWork W2748952813 @default.
- W2023001218 hasRelatedWork W2117909172 @default.
- W2023001218 hasRelatedWork W4253599722 @default.
- W2023001218 hasVolume "5" @default.
- W2023001218 isParatext "false" @default.
- W2023001218 isRetracted "false" @default.
- W2023001218 magId "2023001218" @default.
- W2023001218 workType "article" @default.