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- W2023003876 abstract "Adoptive transfer of helper T (Th) cells conferred a late asthmatic response upon antigen challenge. A possible production of a contractile activity for bronchial smooth muscle (BSM) by activated Th cells was examined.Murine Th clones were stimulated with immobilized anti-CD3 antibody in the presence or absence of anti-CD28 antibody. Culture supernatants were dialyzed and then applied to the collagen gels containing cultured human BSM cells.Culture supernatants of activated but not resting murine Th clones that conferred a late asthmatic response, induced the contraction of human BSM cell-containing collagen gels.Activated Th cells produce a contractile activity for BSM in vitro." @default.
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- W2023003876 date "2012-01-01" @default.
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- W2023003876 title "Murine T Cell-Derived Contractile Activity for Bronchial Smooth Muscle Cells" @default.
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- W2023003876 doi "https://doi.org/10.1159/000337743" @default.
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