FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023006278> ?p ?o ?g. }

• W2023006278 abstract "Variants of the interferon-lambda3 (IFNL3) gene have been associated with both spontaneous and treatment induced clearance of HCV infection. Attempts to link polymorphisms of the IFNL3 gene with variation in the level of IFNL3 expression have been inconclusive. This is partially due to the difficulty to design assays distinguishing IFNL3 from IFNL2. In this study an allele specific real-time PCR (RT-PCR) assay was developed which allows the relative quantification of the two IFNL3 transcripts in cells heterozygous for SNP IFNL3.rs4803217 in the 3'UTR of the IFNL3 gene. This SNP is in strong linkage disequilibrium (LD) with the predictive marker rs12979860. Raji cells showed two-fold increased levels of IFNL3.rs4803217 C-allele expression. In peripheral blood mononuclear cells (PBMCs) of eight uninfected donors, two donors showed increased IFNL3.rs4803217 C-allele expression. This indicates that allele specific differences in IFNL3 expression vary between individuals and might contribute to the variety of outcomes in HCV infected patients." @default.
• W2023006278 created "2016-06-24" @default.
• W2023006278 creator A5001445058 @default.
• W2023006278 creator A5023606749 @default.
• W2023006278 creator A5055046083 @default.
• W2023006278 creator A5082519264 @default.
• W2023006278 creator A5087652027 @default.
• W2023006278 date "2014-10-05" @default.
• W2023006278 modified "2023-10-18" @default.
• W2023006278 title "Detection of allele specific differences in IFNL3 (IL28B)mRNA expression" @default.
• W2023006278 cites W1520176984 @default.
• W2023006278 cites W1910255988 @default.
• W2023006278 cites W1970451495 @default.
• W2023006278 cites W1977927757 @default.
• W2023006278 cites W2005594962 @default.
• W2023006278 cites W2013721785 @default.
• W2023006278 cites W2017013905 @default.
• W2023006278 cites W2017151443 @default.
• W2023006278 cites W2019159816 @default.
• W2023006278 cites W2023528999 @default.
• W2023006278 cites W2024786055 @default.
• W2023006278 cites W2026614040 @default.
• W2023006278 cites W2027148031 @default.
• W2023006278 cites W2046969292 @default.
• W2023006278 cites W2047984410 @default.
• W2023006278 cites W2055102542 @default.
• W2023006278 cites W2058538904 @default.
• W2023006278 cites W2059566143 @default.
• W2023006278 cites W2063285149 @default.
• W2023006278 cites W2064285755 @default.
• W2023006278 cites W2070755355 @default.
• W2023006278 cites W2082588492 @default.
• W2023006278 cites W2086409213 @default.
• W2023006278 cites W2086414517 @default.
• W2023006278 cites W2093270469 @default.
• W2023006278 cites W2102232873 @default.
• W2023006278 cites W2110525565 @default.
• W2023006278 cites W2111357931 @default.
• W2023006278 cites W2128469527 @default.
• W2023006278 cites W2130365449 @default.
• W2023006278 cites W2134574083 @default.
• W2023006278 cites W2156236127 @default.
• W2023006278 cites W2160334536 @default.
• W2023006278 cites W4237269866 @default.
• W2023006278 doi "https://doi.org/10.1186/s12881-014-0104-7" @default.
• W2023006278 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4411934" @default.
• W2023006278 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25287681" @default.
• W2023006278 hasPublicationYear "2014" @default.
• W2023006278 type Work @default.
• W2023006278 sameAs 2023006278 @default.
• W2023006278 citedByCount "6" @default.
• W2023006278 countsByYear W20230062782017 @default.
• W2023006278 countsByYear W20230062782018 @default.
• W2023006278 countsByYear W20230062782019 @default.
• W2023006278 countsByYear W20230062782021 @default.
• W2023006278 countsByYear W20230062782022 @default.
• W2023006278 crossrefType "journal-article" @default.
• W2023006278 hasAuthorship W2023006278A5001445058 @default.
• W2023006278 hasAuthorship W2023006278A5023606749 @default.
• W2023006278 hasAuthorship W2023006278A5055046083 @default.
• W2023006278 hasAuthorship W2023006278A5082519264 @default.
• W2023006278 hasAuthorship W2023006278A5087652027 @default.
• W2023006278 hasBestOaLocation W20230062781 @default.
• W2023006278 hasConcept C104317684 @default.
• W2023006278 hasConcept C135763542 @default.
• W2023006278 hasConcept C137061746 @default.
• W2023006278 hasConcept C139275648 @default.
• W2023006278 hasConcept C153209595 @default.
• W2023006278 hasConcept C180754005 @default.
• W2023006278 hasConcept C197754878 @default.
• W2023006278 hasConcept C202751555 @default.
• W2023006278 hasConcept C203014093 @default.
• W2023006278 hasConcept C35605836 @default.
• W2023006278 hasConcept C54355233 @default.
• W2023006278 hasConcept C86803240 @default.
• W2023006278 hasConceptScore W2023006278C104317684 @default.
• W2023006278 hasConceptScore W2023006278C135763542 @default.
• W2023006278 hasConceptScore W2023006278C137061746 @default.
• W2023006278 hasConceptScore W2023006278C139275648 @default.
• W2023006278 hasConceptScore W2023006278C153209595 @default.
• W2023006278 hasConceptScore W2023006278C180754005 @default.
• W2023006278 hasConceptScore W2023006278C197754878 @default.
• W2023006278 hasConceptScore W2023006278C202751555 @default.
• W2023006278 hasConceptScore W2023006278C203014093 @default.
• W2023006278 hasConceptScore W2023006278C35605836 @default.
• W2023006278 hasConceptScore W2023006278C54355233 @default.
• W2023006278 hasConceptScore W2023006278C86803240 @default.
• W2023006278 hasIssue "1" @default.
• W2023006278 hasLocation W20230062781 @default.
• W2023006278 hasLocation W20230062782 @default.
• W2023006278 hasLocation W20230062783 @default.
• W2023006278 hasLocation W20230062784 @default.
• W2023006278 hasOpenAccess W2023006278 @default.
• W2023006278 hasPrimaryLocation W20230062781 @default.
• W2023006278 hasRelatedWork W2056355462 @default.
• W2023006278 hasRelatedWork W2087075310 @default.
• W2023006278 hasRelatedWork W2157908805 @default.
• W2023006278 hasRelatedWork W2161110446 @default.
• W2023006278 hasRelatedWork W2187968078 @default.
• W2023006278 hasRelatedWork W2283861756 @default.

• next