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- W2023009194 abstract "We present molecular-level simulations of dendrimer/DNA complexes in the presence of a model cell membrane. We determine the required conditions for the complex to arrive intact at the membrane, and the lifetime of the complex as it resides attached to the membrane. Our simulations directly pertain to critical issues arising in emerging gene delivery therapeutic applications, where a molecular carrier is required to deliver DNA segments to the interior of living cells." @default.
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- W2023009194 date "2009-04-16" @default.
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- W2023009194 title "Dendrimers as synthetic gene vectors: Cell membrane attachment" @default.
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- W2023009194 doi "https://doi.org/10.1063/1.3109902" @default.
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