FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023013363> ?p ?o ?g. }

• W2023013363 endingPage "1403" @default.
• W2023013363 startingPage "1403" @default.
• W2023013363 abstract "To date, there is mixed evidence on the safety and effectiveness of tiotropium. Our objective was to evaluate the comparative effectiveness of regimens containing tiotropium bromide vs other medication regimens for chronic obstructive pulmonary disease (COPD) in real-world clinical settings.We conducted a cohort study on 2 separate cohorts with a diagnosis of COPD in the Veterans Affairs health care system. Patients with a diagnosis of COPD prescribed tiotropium and patients in a historic cohort prior to the introduction of tiotropium were selected for comparison using propensity scores, with the base case including scores from 0.1 to 0.4. Outcomes identified during follow-up were all-cause mortality, COPD exacerbations, and COPD hospitalizations. Exposure to COPD medication regimens was defined in a time-varying manner and Cox proportional hazards regression were used to evaluate outcomes.For 42 090 patients in the base case, the regimen of tiotropium + inhaled corticosteroids (ICS) + long-acting beta-agonists (LABA) was associated with 40% reduced risk of death (hazard ratio [HR], 0.60; 95% confidence interval [CI], 0.45-0.79) compared with ICS + LABA. This combination was associated with reduced rates of COPD exacerbations (HR, 0.84; 95% CI, 0.73-0.97) and COPD hospitalizations (HR, 0.78; 95% CI, 0.62-0.98). Tiotropium in combination with 2 other medications was associated with increased risk of mortality, exacerbations, and hospitalizations.When used with ICS and LABA, tiotropium use was associated with a decreased risk of mortality compared with treatment with ICS and LABA. However, this result was not consistent in other medication regimens that included tiotropium [corrected]." @default.
• W2023013363 created "2016-06-24" @default.
• W2023013363 creator A5039522249 @default.
• W2023013363 creator A5046614364 @default.
• W2023013363 creator A5055205242 @default.
• W2023013363 creator A5058888906 @default.
• W2023013363 creator A5065133242 @default.
• W2023013363 creator A5068516928 @default.
• W2023013363 creator A5091576969 @default.
• W2023013363 date "2009-08-10" @default.
• W2023013363 modified "2023-10-18" @default.
• W2023013363 title "Outcomes Associated With Tiotropium Use in Patients With Chronic Obstructive Pulmonary Disease" @default.
• W2023013363 cites W110745020 @default.
• W2023013363 cites W1547708675 @default.
• W2023013363 cites W1692839365 @default.
• W2023013363 cites W1928394001 @default.
• W2023013363 cites W1971649226 @default.
• W2023013363 cites W1978457536 @default.
• W2023013363 cites W1979182385 @default.
• W2023013363 cites W2016053158 @default.
• W2023013363 cites W2025433411 @default.
• W2023013363 cites W2029276834 @default.
• W2023013363 cites W2029516668 @default.
• W2023013363 cites W2031708494 @default.
• W2023013363 cites W2032171019 @default.
• W2023013363 cites W2036712551 @default.
• W2023013363 cites W2042104538 @default.
• W2023013363 cites W2045616259 @default.
• W2023013363 cites W2047636872 @default.
• W2023013363 cites W2051722503 @default.
• W2023013363 cites W2052806549 @default.
• W2023013363 cites W2067764770 @default.
• W2023013363 cites W2068953434 @default.
• W2023013363 cites W2070935883 @default.
• W2023013363 cites W2072205603 @default.
• W2023013363 cites W2074087509 @default.
• W2023013363 cites W2081884196 @default.
• W2023013363 cites W2082034211 @default.
• W2023013363 cites W2102520493 @default.
• W2023013363 cites W2104193617 @default.
• W2023013363 cites W2111714917 @default.
• W2023013363 cites W2113026917 @default.
• W2023013363 cites W2117317003 @default.
• W2023013363 cites W2120378169 @default.
• W2023013363 cites W2121690051 @default.
• W2023013363 cites W2127951128 @default.
• W2023013363 cites W2137478787 @default.
• W2023013363 cites W2141034778 @default.
• W2023013363 cites W2142724633 @default.
• W2023013363 cites W2144711807 @default.
• W2023013363 cites W2153220542 @default.
• W2023013363 cites W2158530076 @default.
• W2023013363 cites W2159062207 @default.
• W2023013363 cites W2164595809 @default.
• W2023013363 cites W2166432084 @default.
• W2023013363 cites W2168639902 @default.
• W2023013363 cites W2171294019 @default.
• W2023013363 cites W2171545556 @default.
• W2023013363 doi "https://doi.org/10.1001/archinternmed.2009.233" @default.
• W2023013363 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19667304" @default.
• W2023013363 hasPublicationYear "2009" @default.
• W2023013363 type Work @default.
• W2023013363 sameAs 2023013363 @default.
• W2023013363 citedByCount "50" @default.
• W2023013363 countsByYear W20230133632012 @default.
• W2023013363 countsByYear W20230133632013 @default.
• W2023013363 countsByYear W20230133632014 @default.
• W2023013363 countsByYear W20230133632015 @default.
• W2023013363 countsByYear W20230133632016 @default.
• W2023013363 countsByYear W20230133632017 @default.
• W2023013363 countsByYear W20230133632018 @default.
• W2023013363 countsByYear W20230133632019 @default.
• W2023013363 countsByYear W20230133632020 @default.
• W2023013363 countsByYear W20230133632021 @default.
• W2023013363 countsByYear W20230133632022 @default.
• W2023013363 crossrefType "journal-article" @default.
• W2023013363 hasAuthorship W2023013363A5039522249 @default.
• W2023013363 hasAuthorship W2023013363A5046614364 @default.
• W2023013363 hasAuthorship W2023013363A5055205242 @default.
• W2023013363 hasAuthorship W2023013363A5058888906 @default.
• W2023013363 hasAuthorship W2023013363A5065133242 @default.
• W2023013363 hasAuthorship W2023013363A5068516928 @default.
• W2023013363 hasAuthorship W2023013363A5091576969 @default.
• W2023013363 hasBestOaLocation W20230133631 @default.
• W2023013363 hasConcept C126322002 @default.
• W2023013363 hasConcept C177713679 @default.
• W2023013363 hasConcept C201903717 @default.
• W2023013363 hasConcept C207103383 @default.
• W2023013363 hasConcept C2776780178 @default.
• W2023013363 hasConcept C2776968687 @default.
• W2023013363 hasConcept C2777714996 @default.
• W2023013363 hasConcept C2781413609 @default.
• W2023013363 hasConcept C3018587741 @default.
• W2023013363 hasConcept C44249647 @default.
• W2023013363 hasConcept C50382708 @default.
• W2023013363 hasConcept C71924100 @default.
• W2023013363 hasConcept C72563966 @default.
• W2023013363 hasConceptScore W2023013363C126322002 @default.

• next