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- W2023015414 abstract "The curve shift method and the brain stimulation reward paradigm were used to dissociate reward and performance changes and determine whether unilateral ICV microinjection of neurotensin (3, 10, and 30 μg10 μl) produces neuroleptic- or psychostimulant-like effect on a dopamine-dependent behavior. At the highest dose tested, neurotensin potentiated brain stimulation reward, producing a significant time-dependent decrease in frequency threshold. Neurotensin also suppressed maximal rate of responding at every dose tested, suggesting that it was more effective at attenuating performance capability. These results suggest that a centrally acting neurotensin receptor agonist may specifically stimulate dopamine-dependent behaviors, producing psychostimulant-like effect that can be attenuated or masked by a suppression of performance capability." @default.
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- W2023015414 date "1995-01-01" @default.
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- W2023015414 title "Psychostimulant-like effect of central microinjection of neurotensin on brain stimulation reward" @default.
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- W2023015414 doi "https://doi.org/10.1016/0196-9781(95)02032-2" @default.
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