Matches in SemOpenAlex for { <https://semopenalex.org/work/W20230162> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W20230162 endingPage "389" @default.
- W20230162 startingPage "385" @default.
- W20230162 abstract "1. Mucositis is a common side-effect of chemotherapy which is difficult to assess except by invasive means such as upper gastrointestinal endoscopy. Differential absorption of mono- and di-saccharides, such as rhamnose and lactulose, is a non-invasive measure of intestinal damage. 2. The purpose of the study was to assess the duration and severity of intestinal damage in patients undergoing high-dose chemotherapy and autologous blood stem-cell transplantation for malignant disease. 3. Thirty-five patients were studied before treatment and at 7, 28, 60 and 90 days after treatment. 4. The median lactulose/rhamnose ratios before treatment and at 7 and 90 days post-treatment were 0.09, 0.62 and 0.06 respectively. Altered permeability was due to both increased lactulose permeation and decreased rhamnose absorption. These abnormalities suggest a defect in tight-junction integrity as well as a decrease in surface area of small bowel. 5. We conclude that chemotherapy given for malignant disease is associated with a transient abnormality in intestinal sugar permeability, which peaks at 7 days after treatment and is composed of both mono- and di-saccharide absorption abnormalities." @default.
- W20230162 created "2016-06-24" @default.
- W20230162 creator A5019022781 @default.
- W20230162 creator A5035752764 @default.
- W20230162 creator A5052972588 @default.
- W20230162 creator A5055550975 @default.
- W20230162 creator A5078611900 @default.
- W20230162 creator A5082239685 @default.
- W20230162 date "1997-04-01" @default.
- W20230162 modified "2023-09-30" @default.
- W20230162 title "Effect of High-Dose Chemotherapy on Intestinal Permeability in Humans" @default.
- W20230162 cites W1965478326 @default.
- W20230162 cites W2009836689 @default.
- W20230162 cites W2011771870 @default.
- W20230162 cites W2059648852 @default.
- W20230162 cites W2092626456 @default.
- W20230162 cites W2124471003 @default.
- W20230162 cites W2130532931 @default.
- W20230162 cites W2257569374 @default.
- W20230162 doi "https://doi.org/10.1042/cs0920385" @default.
- W20230162 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9176038" @default.
- W20230162 hasPublicationYear "1997" @default.
- W20230162 type Work @default.
- W20230162 sameAs 20230162 @default.
- W20230162 citedByCount "136" @default.
- W20230162 countsByYear W202301622012 @default.
- W20230162 countsByYear W202301622013 @default.
- W20230162 countsByYear W202301622014 @default.
- W20230162 countsByYear W202301622015 @default.
- W20230162 countsByYear W202301622016 @default.
- W20230162 countsByYear W202301622017 @default.
- W20230162 countsByYear W202301622018 @default.
- W20230162 countsByYear W202301622019 @default.
- W20230162 countsByYear W202301622020 @default.
- W20230162 countsByYear W202301622021 @default.
- W20230162 countsByYear W202301622022 @default.
- W20230162 countsByYear W202301622023 @default.
- W20230162 crossrefType "journal-article" @default.
- W20230162 hasAuthorship W20230162A5019022781 @default.
- W20230162 hasAuthorship W20230162A5035752764 @default.
- W20230162 hasAuthorship W20230162A5052972588 @default.
- W20230162 hasAuthorship W20230162A5055550975 @default.
- W20230162 hasAuthorship W20230162A5078611900 @default.
- W20230162 hasAuthorship W20230162A5082239685 @default.
- W20230162 hasConcept C100817775 @default.
- W20230162 hasConcept C126322002 @default.
- W20230162 hasConcept C185592680 @default.
- W20230162 hasConcept C2776694085 @default.
- W20230162 hasConcept C2777448540 @default.
- W20230162 hasConcept C2778496288 @default.
- W20230162 hasConcept C2779213145 @default.
- W20230162 hasConcept C2781071285 @default.
- W20230162 hasConcept C2911091166 @default.
- W20230162 hasConcept C55493867 @default.
- W20230162 hasConcept C71924100 @default.
- W20230162 hasConcept C90924648 @default.
- W20230162 hasConceptScore W20230162C100817775 @default.
- W20230162 hasConceptScore W20230162C126322002 @default.
- W20230162 hasConceptScore W20230162C185592680 @default.
- W20230162 hasConceptScore W20230162C2776694085 @default.
- W20230162 hasConceptScore W20230162C2777448540 @default.
- W20230162 hasConceptScore W20230162C2778496288 @default.
- W20230162 hasConceptScore W20230162C2779213145 @default.
- W20230162 hasConceptScore W20230162C2781071285 @default.
- W20230162 hasConceptScore W20230162C2911091166 @default.
- W20230162 hasConceptScore W20230162C55493867 @default.
- W20230162 hasConceptScore W20230162C71924100 @default.
- W20230162 hasConceptScore W20230162C90924648 @default.
- W20230162 hasIssue "4" @default.
- W20230162 hasLocation W202301621 @default.
- W20230162 hasLocation W202301622 @default.
- W20230162 hasOpenAccess W20230162 @default.
- W20230162 hasPrimaryLocation W202301621 @default.
- W20230162 hasRelatedWork W1525871018 @default.
- W20230162 hasRelatedWork W1966040449 @default.
- W20230162 hasRelatedWork W1978332406 @default.
- W20230162 hasRelatedWork W2007481610 @default.
- W20230162 hasRelatedWork W2028926869 @default.
- W20230162 hasRelatedWork W2064958296 @default.
- W20230162 hasRelatedWork W2078673484 @default.
- W20230162 hasRelatedWork W2434087271 @default.
- W20230162 hasRelatedWork W2465662249 @default.
- W20230162 hasRelatedWork W3100501994 @default.
- W20230162 hasVolume "92" @default.
- W20230162 isParatext "false" @default.
- W20230162 isRetracted "false" @default.
- W20230162 magId "20230162" @default.
- W20230162 workType "article" @default.