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- W2023017409 abstract "Phase-transfer glycosylation of 4-chloro-1H-pyrazolo[3,4-d]pyrimidine (1) with 2-deoxy-3,5-di-O-(p-toluoyl)-α-D-erythro-pentofuranosyl chloride (2) yielded the N-1 glycosylation product (3) in 42%. The protected intermediate (3) was converted into pyrazolo[3,4-d]pyrimidine 2′-deoxyribofuranosides with amino, oxo, and thioxo substituents at C-4. Kinetic data of proton-catalysed hydrolysis showed that pyrazolo[3,4-d]pyrimidine 2′-deoxyribofuranosides are more stable at the N-glycosylic bond than are the parent purine nucleosides." @default.
- W2023017409 created "2016-06-24" @default.
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- W2023017409 date "1985-01-01" @default.
- W2023017409 modified "2023-10-09" @default.
- W2023017409 title "Synthesis and hydrolytic stability of 4-substituted pyrazolo[3,4-d]pyrimidine 2′-deoxyribofuranosides" @default.
- W2023017409 doi "https://doi.org/10.1039/p19850002573" @default.
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