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- W2023031211 abstract "Abstract [3 H]Adrenaline was incorporated in an isolated perfused preparation of the rabbit adrenal gland and the effects of indomethacin, PGE2 and PGI2 on its release were investigated. Efflux of [3 H]adrenaline was elicited by electrical stimulation of the splanchnic nerve (60 s at 5 Hz). Indomethacin (3 and 30 μM) had no effect on stimulation-induced efflux. PGE2 (30, 90 and 300 nM) reduced the efflux; with 90 nM PGE2 the inhibition amounted to approximately 30%. PGI2, in concentrations from 90 to 600 nM, was without effect. These findings indicate that release of [3 H]adrenaline from the rabbit adrenal gland is not subject to modulation by endogenous adrenal prostaglandins; however, PGE2 may play a role in some pathological situations." @default.
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- W2023031211 date "1985-03-01" @default.
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- W2023031211 title "Prostanoids and adrenaline release: a study of [3 H]adrenaline efflux from the rabbit isolated, perfused, adrenal gland" @default.
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- W2023031211 doi "https://doi.org/10.1111/j.2042-7158.1985.tb05037.x" @default.
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