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- W2023085878 abstract "Calcineurin B-like (CBL) proteins represent a unique family of calcium sensors in plant cells. Sensing the calcium signals elicited by a variety of abiotic stresses, CBLs transmit the information to a group of serine/threonine protein kinases (CBL-interacting protein kinases [CIPKs]), which are currently known as the sole targets of the CBL family. Here, we report that the CBL3 member of this family has a novel interaction partner in addition to the CIPK proteins. Extensive yeast two-hybrid screenings with CBL3 as bait identified an interesting Arabidopsis (Arabidopsis thaliana) cDNA clone (named AtMTAN, for 5'-methylthioadenosine nucleosidase), which encodes a polypeptide similar to EcMTAN from Escherichia coli. Deletion analyses showed that CBL3 utilizes the different structural modules to interact with its distinct target proteins, CIPKs and AtMTAN. In vitro and in vivo analyses verified that CBL3 and AtMTAN physically associate only in the presence of Ca(2+). In addition, we empirically demonstrated that the AtMTAN protein indeed possesses the MTAN activity, which can be inhibited specifically by Ca(2+)-bound CBL3. Overall, these findings suggest that the CBL family members can relay the calcium signals in more diverse ways than previously thought. We also discuss a possible mechanism by which the CBL3-mediated calcium signaling regulates the biosynthesis of ethylene and polyamines, which are involved in plant growth and development as well as various stress responses." @default.
- W2023085878 created "2016-06-24" @default.
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- W2023085878 date "2008-10-22" @default.
- W2023085878 modified "2023-10-10" @default.
- W2023085878 title "The Arabidopsis Calcium Sensor Calcineurin B-Like 3 Inhibits the 5′-Methylthioadenosine Nucleosidase in a Calcium-Dependent Manner " @default.
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- W2023085878 cites W1539503448 @default.
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- W2023085878 cites W1589171339 @default.
- W2023085878 cites W1590772095 @default.
- W2023085878 cites W1972139105 @default.
- W2023085878 cites W1973718080 @default.
- W2023085878 cites W1985001103 @default.
- W2023085878 cites W1991334987 @default.
- W2023085878 cites W1992211373 @default.
- W2023085878 cites W2004006914 @default.
- W2023085878 cites W2007405937 @default.
- W2023085878 cites W2010978356 @default.
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- W2023085878 cites W2014194256 @default.
- W2023085878 cites W2016174913 @default.
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- W2023085878 cites W2019682502 @default.
- W2023085878 cites W2020784047 @default.
- W2023085878 cites W2024249829 @default.
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- W2023085878 cites W2049499418 @default.
- W2023085878 cites W2058762917 @default.
- W2023085878 cites W2060033205 @default.
- W2023085878 cites W2077355527 @default.
- W2023085878 cites W2080017573 @default.
- W2023085878 cites W2091028716 @default.
- W2023085878 cites W2093601203 @default.
- W2023085878 cites W2098769040 @default.
- W2023085878 cites W2102323998 @default.
- W2023085878 cites W2104062741 @default.
- W2023085878 cites W2104417055 @default.
- W2023085878 cites W2105474942 @default.
- W2023085878 cites W2105618655 @default.
- W2023085878 cites W2114595347 @default.
- W2023085878 cites W2115595638 @default.
- W2023085878 cites W2116122104 @default.
- W2023085878 cites W2116755872 @default.
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- W2023085878 cites W2128635872 @default.
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- W2023085878 cites W2142946131 @default.
- W2023085878 cites W2145048774 @default.
- W2023085878 cites W2146430471 @default.
- W2023085878 cites W2150015388 @default.
- W2023085878 cites W2152561884 @default.
- W2023085878 cites W2152801147 @default.
- W2023085878 cites W2153216467 @default.
- W2023085878 cites W2153475422 @default.
- W2023085878 cites W2156750195 @default.
- W2023085878 cites W2161704630 @default.
- W2023085878 cites W2162522352 @default.
- W2023085878 cites W2167255717 @default.
- W2023085878 cites W2174475512 @default.
- W2023085878 cites W2188177493 @default.
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- W2023085878 doi "https://doi.org/10.1104/pp.108.130419" @default.
- W2023085878 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2593668" @default.
- W2023085878 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18945934" @default.
- W2023085878 hasPublicationYear "2008" @default.
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