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- W2023102502 abstract "The present study investigates the role of cGMP and cAMP on the memory performance in the object recognition task in rats. The analogue 8-Br-GMP or 8-Br-cAMP was administered bilaterally into the hippocampus (0, 1, 3 and 10 microg in 0.5 microl saline/site) immediately after the exposure to two identical objects. After 24 h, saline-treated animals spent equal times exploring a new and the familiar object demonstrating that they did not recognize the familiar one. However, a dose-dependent improvement in object recognition was found after injection of 8-Br-cGMP. In contrast, 8-Br-cAMP did not improve the memory performance at the doses tested. These results indicate that hippocampal cGMP but not cAMP is involved in early stages of consolidation of object memory." @default.
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- W2023102502 date "2002-02-01" @default.
- W2023102502 modified "2023-09-27" @default.
- W2023102502 title "cGMP, but not cAMP, in rat hippocampus is involved in early stages of object memory consolidation" @default.
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- W2023102502 doi "https://doi.org/10.1016/s0014-2999(01)01614-4" @default.
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