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• W2023105385 abstract "Chronic hepatitis C virus (HCV) infection is common in hemodialysis (HD) patients. In the present study, the prevalence and properties of HCV in HD patients were analyzed.Of 125 HD patients, 34 (27%) were positive for antibody to HCV, and HCV-RNA was detected in 23 (68%) of the 34 patients using reverse transcription polymerase chain reaction. The HCV-RNA sequence analysis did not identify the alterations specific to HD patients with HCV, although one patient had a variant virus containing the deletion of the core gene sequence. When serial changes in the levels of HCV-RNA were evaluated in 15 patients by a branched DNA assay, the values decreased immediately after HD procedure, but returned to the baseline values 2 days after the procedure.These results indicate that HCV in HD patients is replication-competent, although a transient reduction in the levels of HCV-RNA occurs during HD." @default.
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• W2023105385 date "1999-01-01" @default.
• W2023105385 modified "2023-09-26" @default.
• W2023105385 title "Prevalence and Characterization of Hepatitis C Virus in Hemodialysis Patients." @default.
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• W2023105385 doi "https://doi.org/10.2169/internalmedicine.38.626" @default.
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