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• W2023115100 abstract "To ascertain the effect of obesity-related inflammation on maternal and fetal iron status. We hypothesized that obese (Ob) pregnant women would have increased inflammation, hepcidin levels, and that their infants would have impaired iron status compared with lean (Lc) controls. Fifteen Ob and fifteen Lc women were recruited in their second trimester of pregnancy. Markers of iron status, inflammation and hepcidin were measured in maternal and cord blood. Student's t-test was used to compare Ob and Lc groups, and Pearson's correlation coefficients were determined between maternal and cord blood values. Maternal C-reactive protein (P<0.01) and hepcidin (P<0.01) were higher, and cord blood iron (P<0.01) was lower in the Ob group. Maternal body mass index (P<0.01) and hepcidin (P<0.05) were negatively correlated with cord blood iron status. Maternal obesity is associated with impaired maternal-fetal iron transfer, potentially through hepcidin upregulation." @default.
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• W2023115100 date "2012-06-21" @default.
• W2023115100 modified "2023-10-16" @default.
• W2023115100 title "Obesity during pregnancy and fetal iron status: is Hepcidin the link?" @default.
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• W2023115100 doi "https://doi.org/10.1038/jp.2012.81" @default.
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