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- W2023130054 abstract "We present a long-surviving patient with Wiskott-Aldrich syndrome complicated by atypical progressive multifocal leukoencephalopathy (PML). MRI showed multiple tiny spots of Gd-DTPA-enhanced lesions on the T<sub>1</sub>-weighted image. Pathologic findings for brain biopsy were patchy demyelinated vascularized lesions infiltrated by a surprising number of eosinophils. The presence of polyomavirus JC was confirmed by in situ hybridization and polymerase chain reaction. PML should be included in the differential diagnosis when Gd-DTPA-enhanced spotty lesions are present in the white matter, especially in patients who have a mild immunologic defect. <b>NEUROLOGY 1997;48: </b> 279-282" @default.
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- W2023130054 date "1997-01-01" @default.
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- W2023130054 title "Unusual MRI and Pathologic Findings of Progressive Multifocal Leukoencephalopathy Complicating Adult Wiskott-Aldrich Syndrome" @default.
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- W2023130054 doi "https://doi.org/10.1212/wnl.48.1.279" @default.
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