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- W2023135395 abstract "Lithotripter fields can produce cavitation in the organs of the body at pressure amplitudes significantly lower than those required to fragment stones. Because of limits on the expansion of the gaseous nuclei imposed by the surrounding tissue structures, cavitation in tissue is qualitatively different from that described by classical cavitation theory for a spherical bubble in an infinite fluid. Thresholds for structural and functional changes in kidney, liver, lung, heart, and blood, developmental effects in the embryo/fetus, and killing of Drosophilia larvae have been determined. Studies of the biological effects of shock waves generated by lithotripters have guided us in the search for effects of diagnostically relevant pulsed ultrasound. In particular, lung hemorrhage occurs with pulsed ultrasound at acoustic pressures of the order of 1 MPa and effects on the dynamic behavior of heart tissue have been seen with single 1–10 ms pulses at pressure amplitudes of the order of 10 MPa. The effects in lung occur at temporal average intensities orders of magnitude lower than previously associated with biological effects in mammals." @default.
- W2023135395 created "2016-06-24" @default.
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- W2023135395 date "1992-04-01" @default.
- W2023135395 modified "2023-09-24" @default.
- W2023135395 title "Cavitation bioeffects: Spin‐offs from lithotripsy." @default.
- W2023135395 doi "https://doi.org/10.1121/1.403155" @default.
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