Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023137124> ?p ?o ?g. }
- W2023137124 endingPage "476" @default.
- W2023137124 startingPage "472" @default.
- W2023137124 abstract "Spider silks are protein-based “biopolymer” filaments or threads secreted by specialized epithelial cells as concentrated soluble precursors of highly repetitive primary sequences. Spider dragline silk is a flexible, lightweight fiber of extraordinary strength and toughness comparable to that of synthetic high-performance fibers. We sought to “biomimic” the process of spider silk production by expressing in mammalian cells the dragline silk genes ( ADF-3 / MaSpII and MaSpI ) of two spider species. We produced soluble recombinant (rc)–dragline silk proteins with molecular masses of 60 to 140 kilodaltons. We demonstrated the wet spinning of silk monofilaments spun from a concentrated aqueous solution of soluble rc–spider silk protein (ADF-3; 60 kilodaltons) under modest shear and coagulation conditions. The spun fibers were water insoluble with a fine diameter (10 to 40 micrometers) and exhibited toughness and modulus values comparable to those of native dragline silks but with lower tenacity. Dope solutions with rc–silk protein concentrations >20% and postspinning draw were necessary to achieve improved mechanical properties of the spun fibers. Fiber properties correlated with finer fiber diameter and increased birefringence." @default.
- W2023137124 created "2016-06-24" @default.
- W2023137124 creator A5017266675 @default.
- W2023137124 creator A5019657745 @default.
- W2023137124 creator A5029831427 @default.
- W2023137124 creator A5053234929 @default.
- W2023137124 creator A5058552757 @default.
- W2023137124 creator A5070600137 @default.
- W2023137124 creator A5078375350 @default.
- W2023137124 creator A5084685591 @default.
- W2023137124 creator A5084714177 @default.
- W2023137124 date "2002-01-18" @default.
- W2023137124 modified "2023-10-16" @default.
- W2023137124 title "Spider Silk Fibers Spun from Soluble Recombinant Silk Produced in Mammalian Cells" @default.
- W2023137124 cites W1542008397 @default.
- W2023137124 cites W1658845344 @default.
- W2023137124 cites W1964448580 @default.
- W2023137124 cites W1968087748 @default.
- W2023137124 cites W1982331202 @default.
- W2023137124 cites W1987048516 @default.
- W2023137124 cites W1991893727 @default.
- W2023137124 cites W1992516996 @default.
- W2023137124 cites W1996895964 @default.
- W2023137124 cites W1999270493 @default.
- W2023137124 cites W2000550628 @default.
- W2023137124 cites W2006774934 @default.
- W2023137124 cites W2016585396 @default.
- W2023137124 cites W2018380333 @default.
- W2023137124 cites W2029033315 @default.
- W2023137124 cites W2047740897 @default.
- W2023137124 cites W2057689611 @default.
- W2023137124 cites W2066626466 @default.
- W2023137124 cites W2085830562 @default.
- W2023137124 cites W2088084607 @default.
- W2023137124 cites W2092130438 @default.
- W2023137124 cites W2096922307 @default.
- W2023137124 cites W2099706338 @default.
- W2023137124 cites W2127555424 @default.
- W2023137124 cites W2161826643 @default.
- W2023137124 cites W2262929344 @default.
- W2023137124 cites W2528886449 @default.
- W2023137124 cites W2541050244 @default.
- W2023137124 cites W2907453578 @default.
- W2023137124 cites W2907521293 @default.
- W2023137124 cites W2907582783 @default.
- W2023137124 doi "https://doi.org/10.1126/science.1065780" @default.
- W2023137124 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11799236" @default.
- W2023137124 hasPublicationYear "2002" @default.
- W2023137124 type Work @default.
- W2023137124 sameAs 2023137124 @default.
- W2023137124 citedByCount "607" @default.
- W2023137124 countsByYear W20231371242012 @default.
- W2023137124 countsByYear W20231371242013 @default.
- W2023137124 countsByYear W20231371242014 @default.
- W2023137124 countsByYear W20231371242015 @default.
- W2023137124 countsByYear W20231371242016 @default.
- W2023137124 countsByYear W20231371242017 @default.
- W2023137124 countsByYear W20231371242018 @default.
- W2023137124 countsByYear W20231371242019 @default.
- W2023137124 countsByYear W20231371242020 @default.
- W2023137124 countsByYear W20231371242021 @default.
- W2023137124 countsByYear W20231371242022 @default.
- W2023137124 countsByYear W20231371242023 @default.
- W2023137124 crossrefType "journal-article" @default.
- W2023137124 hasAuthorship W2023137124A5017266675 @default.
- W2023137124 hasAuthorship W2023137124A5019657745 @default.
- W2023137124 hasAuthorship W2023137124A5029831427 @default.
- W2023137124 hasAuthorship W2023137124A5053234929 @default.
- W2023137124 hasAuthorship W2023137124A5058552757 @default.
- W2023137124 hasAuthorship W2023137124A5070600137 @default.
- W2023137124 hasAuthorship W2023137124A5078375350 @default.
- W2023137124 hasAuthorship W2023137124A5084685591 @default.
- W2023137124 hasAuthorship W2023137124A5084714177 @default.
- W2023137124 hasConcept C126348684 @default.
- W2023137124 hasConcept C154815118 @default.
- W2023137124 hasConcept C159985019 @default.
- W2023137124 hasConcept C192562407 @default.
- W2023137124 hasConcept C2776844667 @default.
- W2023137124 hasConcept C2776847223 @default.
- W2023137124 hasConcept C2778636629 @default.
- W2023137124 hasConcept C2780181586 @default.
- W2023137124 hasConcept C2780431358 @default.
- W2023137124 hasConcept C519885992 @default.
- W2023137124 hasConcept C521977710 @default.
- W2023137124 hasConcept C64208038 @default.
- W2023137124 hasConcept C86803240 @default.
- W2023137124 hasConcept C90856448 @default.
- W2023137124 hasConcept C99595764 @default.
- W2023137124 hasConceptScore W2023137124C126348684 @default.
- W2023137124 hasConceptScore W2023137124C154815118 @default.
- W2023137124 hasConceptScore W2023137124C159985019 @default.
- W2023137124 hasConceptScore W2023137124C192562407 @default.
- W2023137124 hasConceptScore W2023137124C2776844667 @default.
- W2023137124 hasConceptScore W2023137124C2776847223 @default.
- W2023137124 hasConceptScore W2023137124C2778636629 @default.
- W2023137124 hasConceptScore W2023137124C2780181586 @default.
- W2023137124 hasConceptScore W2023137124C2780431358 @default.
- W2023137124 hasConceptScore W2023137124C519885992 @default.