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• W2023137532 endingPage "163" @default.
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• W2023137532 abstract "Profound and multifaceted effects of hormones on the development, maturation and function of the CNS are well documented. Recent developments in magnetic resonance imagining (MRI) and positron emission tomography (PET) permit detailed in vivo studies of cerebral structure and function in humans. Techniques to measure subtle differences in cerebral structure, regional brain activation, changes in blood flow and other physiological biomarkers allow us to translate experimental evidence of hormone effects obtained from animal models to humans. Here we review the imaging techniques available to support studies of hormone effects on the CNS, emphasizing the recent developments of MRI. In summarizing the major current studies we discuss the potential of these techniques for an emerging new field in endocrinology. Profound and multifaceted effects of hormones on the development, maturation and function of the CNS are well documented. Recent developments in magnetic resonance imagining (MRI) and positron emission tomography (PET) permit detailed in vivo studies of cerebral structure and function in humans. Techniques to measure subtle differences in cerebral structure, regional brain activation, changes in blood flow and other physiological biomarkers allow us to translate experimental evidence of hormone effects obtained from animal models to humans. Here we review the imaging techniques available to support studies of hormone effects on the CNS, emphasizing the recent developments of MRI. In summarizing the major current studies we discuss the potential of these techniques for an emerging new field in endocrinology. hemoglobin forms an unstable, reversible bond with oxygen. In its oxygen-unloaded form it is termed deoxyhemoglobin. common non-genetic obesity, body mass index >30. a non-invasive, non-ionizing imaging method that uses powerful magnetic fields to align the magnetization of atoms within the body, and radiofrequency fields to alter the alignment of this magnetization, causing the production of a magnetic field used to construct an image of the scanned area of the body. an acetylated derivative of aspartate found in the brain. Used as a marker of neuronal density in brain magnetic resonance imaging. continuous performance task to assess working memory testing recall of a series of images or words in a sequence; for example, where the participant is asked to recall the third previous word. an imaging technique using positron-emitting radioisotopes attached to metabolic compounds. The annihilation of the positron into gamma rays allows accurate detection of the location of the molecules, and permits the measurement of activity in different parts of the brain – including blood flow and concentrations of substances such as oxygen and glucose. spin-lattice relaxation time, known as T1, is a time constant in MRI. T2 is the spin–spin relaxation time. transverse relaxation time in MRI. volumetric pixels, the smallest spatial unit that a scanner is able to resolve. They are values in a regular grid in 3D space analogous to 2D pixels." @default.
• W2023137532 created "2016-06-24" @default.
• W2023137532 creator A5007903161 @default.
• W2023137532 creator A5015947439 @default.
• W2023137532 creator A5028246201 @default.
• W2023137532 creator A5061471365 @default.
• W2023137532 date "2011-05-01" @default.
• W2023137532 modified "2023-09-27" @default.
• W2023137532 title "Visualizing hormone actions in the brain" @default.
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