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- W2023149817 abstract "The human glycine receptor subtypes α1β and α2 have been expressed stably in HEK293 cells, and the functional characteristics of the receptors have been characterised in the FLIPR® Membrane Potential Assay. The pharmacological properties obtained for nine standard ligands at the two receptors in this assay were found to be in good agreement with those from electrophysiology studies of the receptors expressed in Xenopus oocytes or mammalian cell lines. Hence, this high throughput screening assay will be of great use in future pharmacological studies of glycine receptors, particular in the search for novel compound structures acting at them." @default.
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- W2023149817 date "2005-10-01" @default.
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- W2023149817 title "Functional characterisation of human glycine receptors in a fluorescence-based high throughput screening assay" @default.
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- W2023149817 doi "https://doi.org/10.1016/j.ejphar.2005.08.002" @default.
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